Literature DB >> 33858204

Neonatal coagulopathies: A review of established and emerging treatments.

Nina Moiseiwitsch1,2, Ashley C Brown1,2.   

Abstract

Despite the relative frequency of both bleeding and clotting disorders among patients treated in the neonatal intensive care unit, few clear guidelines exist for treatment of neonatal coagulopathies. The study and treatment of neonatal coagulopathies are complicated by the distinct hemostatic balance and clotting components present during this developmental stage as well as the relative scarcity of studies specific to this age group. This mini-review examines the current understanding of neonatal hemostatic balance and treatment of neonatal coagulopathies, with particular emphasis on emerging treatment methods and areas in need of further investigative efforts.

Entities:  

Keywords:  Neonatal; coagulopathy; developmental hemostasis; transfusion

Mesh:

Year:  2021        PMID: 33858204      PMCID: PMC8243218          DOI: 10.1177/15353702211006046

Source DB:  PubMed          Journal:  Exp Biol Med (Maywood)        ISSN: 1535-3699


  75 in total

Review 1.  Guideline on the management of haemophilia in the fetus and neonate.

Authors:  Elizabeth Chalmers; Michael Williams; Janet Brennand; Ri Liesner; Peter Collins; Michael Richards
Journal:  Br J Haematol       Date:  2011-05-09       Impact factor: 6.998

Review 2.  Neonatal Hemostatic Disorders: Issues and Challenges.

Authors:  Santosh S Hanmod; Rohith Jesudas; Roshni Kulkarni; Meera Chitlur
Journal:  Semin Thromb Hemost       Date:  2016-10-05       Impact factor: 4.180

3.  The efficacy of tranexamic acid versus placebo in decreasing blood loss in pediatric patients undergoing repeat cardiac surgery.

Authors:  R W Reid; A A Zimmerman; P C Laussen; J E Mayer; J B Gorlin; F A Burrows
Journal:  Anesth Analg       Date:  1997-05       Impact factor: 5.108

4.  Activated prothrombin complex concentrates for the reversal of anticoagulant-associated coagulopathy.

Authors:  Nadia I Awad; Craig Cocchio
Journal:  P T       Date:  2013-11

Review 5.  Neonatal thrombocytopenia: causes and management.

Authors:  I Roberts; N A Murray
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2003-09       Impact factor: 5.747

6.  Antithrombin III supplementation on extracorporeal membrane oxygenation: impact on heparin dose and circuit life.

Authors:  Jonathan W Byrnes; Christopher J Swearingen; Parthak Prodhan; Richard Fiser; Umesh Dyamenahalli
Journal:  ASAIO J       Date:  2014 Jan-Feb       Impact factor: 2.872

7.  Development of the human coagulation system in the full-term infant.

Authors:  M Andrew; B Paes; R Milner; M Johnston; L Mitchell; D M Tollefsen; P Powers
Journal:  Blood       Date:  1987-07       Impact factor: 22.113

Review 8.  Developmental hemostasis: laboratory and clinical implications.

Authors:  P Toulon
Journal:  Int J Lab Hematol       Date:  2016-05       Impact factor: 2.877

9.  Neonatal Gene Therapy for Hemophilia B by a Novel Adenovirus Vector Showing Reduced Leaky Expression of Viral Genes.

Authors:  Shunsuke Iizuka; Fuminori Sakurai; Masashi Tachibana; Kazuo Ohashi; Hiroyuki Mizuguchi
Journal:  Mol Ther Methods Clin Dev       Date:  2017-07-08       Impact factor: 6.698

Review 10.  Kasabach-Merritt Phenomenon: Classic Presentation and Management Options.

Authors:  Priya Mahajan; Judith Margolin; Ionela Iacobas
Journal:  Clin Med Insights Blood Disord       Date:  2017-03-16
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