Literature DB >> 33855863

Increasing access to quality anticancer medicines in low- and middle-income countries: the experience of Uganda.

Godfrey Osinde1, Nixon Niyonzima1,2,3, Vivienne Mulema4, Deo Kyambadde1, Yusuf Mulumba1, Siraj Obayo1, Ezra Anecho1, Susan Watera1, Mughuma Constance1, Sylivestor Kadhumbula1, Jackson Orem1,3.   

Abstract

Cancer is one of the leading causes of death with 9.6 million deaths registered in 2018, of which 70% occur in Africa, Asia and Central and South America, the low-and middle-income countries (LMICs). The global annual expenditure on anticancer medicines increased from $96 billion in 2013 to $133 billion in 2017. This growth rate is several folds that of newly diagnosed cancer cases and therefore estimated to reach up to $200 billion by 2022. The Uganda Cancer Institute, Uganda's national referral cancer center, has increased access to cancer medicines through an efficient and cost-saving procurement system. The system has achieved cost savings of more than USD 2,000,000 on a total of 37 of 42 essential cancer medicines. This has resulted in 85.8% availability superseding the WHO's 80% target. All selected products were procured from manufacturers with stringent regulatory authority approval or a proven track record of quality products.

Entities:  

Keywords:  access initiatives; access to medicines; cancer; highly specialized drugs; low- and middle-income countries; minimum order quantity

Mesh:

Substances:

Year:  2021        PMID: 33855863      PMCID: PMC8819588          DOI: 10.2217/fon-2021-0117

Source DB:  PubMed          Journal:  Future Oncol        ISSN: 1479-6694            Impact factor:   3.674


  14 in total

1.  GLOBOCAN 2018: counting the toll of cancer.

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Review 2.  Oncology drugs in the crosshairs of pharmaceutical crime.

Authors:  Bastiaan J Venhuis; Angela E Oostlander; Domenico Di Giorgio; Ruth Mosimann; Ines du Plessis
Journal:  Lancet Oncol       Date:  2018-04       Impact factor: 41.316

Review 3.  The high price of anticancer drugs: origins, implications, barriers, solutions.

Authors:  Vinay Prasad; Kevin De Jesús; Sham Mailankody
Journal:  Nat Rev Clin Oncol       Date:  2017-03-14       Impact factor: 66.675

Review 4.  Public health interventions to protect against falsified medicines: a systematic review of international, national and local policies.

Authors:  William L Hamilton; Cormac Doyle; Mycroft Halliwell-Ewen; Gabriel Lambert
Journal:  Health Policy Plan       Date:  2016-06-16       Impact factor: 3.344

5.  Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.

Authors:  Freddie Bray; Jacques Ferlay; Isabelle Soerjomataram; Rebecca L Siegel; Lindsey A Torre; Ahmedin Jemal
Journal:  CA Cancer J Clin       Date:  2018-09-12       Impact factor: 508.702

6.  Strengthening Laboratory Diagnostic Capacity to Support Cancer Care in Uganda.

Authors:  Nixon Niyonzima; Henry Wannume; Sylivestor Kadhumbula; Hassan Wasswa; Godfrey Osinde; Yusuf Mulumba; Tobias Tusabe; Samuel Kalungi; Jackson Orem
Journal:  Am J Clin Pathol       Date:  2021-07-06       Impact factor: 2.493

7.  Essential medicines for cancer: WHO recommendations and national priorities.

Authors:  Jane Robertson; Ronald Barr; Lawrence N Shulman; Gilles B Forte; Nicola Magrini
Journal:  Bull World Health Organ       Date:  2016-07-05       Impact factor: 9.408

8.  The impact of pricing strategy on the costs of oral anti-cancer drugs.

Authors:  Judy Truong; Kelvin K W Chan; Helen Mai; Alexandra Chambers; Mona Sabharwal; Maureen E Trudeau; Matthew C Cheung
Journal:  Cancer Med       Date:  2019-05-27       Impact factor: 4.452

Review 9.  Substandard drugs: a potential crisis for public health.

Authors:  Atholl Johnston; David W Holt
Journal:  Br J Clin Pharmacol       Date:  2014-08       Impact factor: 4.335

10.  A global comparison of the cost of patented cancer drugs in relation to global differences in wealth.

Authors:  Salomon M Stemmer; Eli Rosenbaum; Daniel A Goldstein; Jonathon Clark; Yifan Tu; Jie Zhang; Fenqi Fang; Robert Goldstein
Journal:  Oncotarget       Date:  2017-05-09
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