Literature DB >> 33854936

Mycobacterium fortuitum and Mycobacterium abscessus infections in the foot and ankle in two immunocompetent patients.

Khai Phang Wong1, Zhi Hao Tang1, Gek Meng Tan1.   

Abstract

Nontuberculous mycobacteria (NTM) infections of the musculoskeletal system are commonly missed due to its rarity and the absence of systemic symptoms. A high clinical index of suspicion is required to recognize such infections as they may occur in immunocompetent hosts. We present two cases of foot and ankle NTM infections involving Mycobacterium fortuitum and Mycobacterium abscessus in two such patients. The first case involves an 83-year old lady who presented with a two-month history of multiple foot abscesses initially treated at a rural hospital. She underwent drainage and debridement of her foot, with eventual cultures growing Pseudomonas aeruginosa and Mycobacterium abscessus. She was initially treated with clarithromycin and doxycycline. At one year follow-up review, her wound healed completely. The second case involves a 55-year old man who presented with infection following midfoot fusion and anterolateral thigh flap for an open complex fracture dislocation of his right foot. Cultures eventually grew Mycobacterium fortuitum and he was treated with cefoxitin, clarithromycin and doxycycline. 10 months after his initial injury, the infection has cleared and his flap was clean. Through these 2 cases, we hope to highlight the unusual presentations of such infections and illustrate that with a high initial index of suspicion and appropriate treatment, these infections can be treated successfully. © the Author(s).

Entities:  

Keywords:  conventional chemotherapy; musculoskeletal infections; nontuberculous mycobacteria; osteomyelitis; septic arthritis

Year:  2020        PMID: 33854936      PMCID: PMC7735975          DOI: 10.37796/2211-8039.1021

Source DB:  PubMed          Journal:  Biomedicine (Taipei)        ISSN: 2211-8020


  14 in total

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Authors:  J E Booth; J A Jacobson; T A Kurrus; T W Edwards
Journal:  J Bone Joint Surg Am       Date:  1979-03       Impact factor: 5.284

6.  Non-tuberculous mycobacterial infection of the musculoskeletal system: pattern of infection and efficacy of combined surgical/antimicrobial treatment.

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8.  Mycobacterium tuberculosis and Mycobacterium fortuitum osteomyelitis of the foot and septic arthritis of the ankle in an immunocompetent patient.

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Journal:  Eur J Clin Microbiol Infect Dis       Date:  2002-06-11       Impact factor: 3.267

9.  Mycobacterium fortuitum infection following total knee arthroplasty: a case report and literature review.

Authors:  Ian Cheung; Anthony Wilson
Journal:  Knee       Date:  2007-09-14       Impact factor: 2.199

10.  Profiling non-tuberculous mycobacteria in an Asian setting: characteristics and clinical outcomes of hospitalized patients in Singapore.

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Journal:  BMC Pulm Med       Date:  2018-05-22       Impact factor: 3.317

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  1 in total

1.  Mycobacterium fortuitum osteomyelitis of the cuboid bone treated with CERAMENT G and V: a case report.

Authors:  Kilian Fraga; Miriam Maireles; Marc Jordan; Laura Soldevila; Oscar Murillo
Journal:  J Bone Jt Infect       Date:  2022-07-25
  1 in total

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