Literature DB >> 3385446

Cerebellar dysfunction in patients with bronchogenic carcinoma: immunological investigations.

K Wessel1, C Budde-Steffen, H Wiethölter, H C Diener, J Dichgans.   

Abstract

Sera from seven patients with bronchogenic carcinoma and cerebellar dysfunction were tested for anti-Purkinje cell antibodies (APCA) by indirect immunofluorescence and indirect immunoperoxidase reaction. Specific APCA as described in paraneoplastic cerebellar degeneration (PCD) were not detected in any of these patients or in control patients. The lack of APCA in patients with bronchogenic carcinoma and their presence in association with ovarian or breast cancer indicate that different pathogenetic mechanisms may play a role in PCD.

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Year:  1988        PMID： 3385446     DOI： 10.1007/bf00314177

Source DB:  PubMed          Journal:  J Neurol        ISSN： 0340-5354            Impact factor:   4.849


  9 in total

1.  Antibodies to brain proteins in paraneoplastic cerebellar degeneration.

Authors:  K Tanaka; M Yamazaki; S Sato; I Toyoshima; A Yamamoto; T Miyatake
Journal:  Neurology       Date:  1986-09       Impact factor: 9.910

2.  Neuronal antinuclear antibody in sensory neuronopathy from lung cancer.

Authors:  F Graus; C Cordon-Cardo; J B Posner
Journal:  Neurology       Date:  1985-04       Impact factor: 9.910

Review 3.  Lambert-Eaton myasthenic syndrome.

Authors:  J Newsom-Davis
Journal:  Springer Semin Immunopathol       Date:  1985

4.  Cerebellar degeneration with Hodgkin disease. An immunological study.

Authors:  J L Trotter; B A Hendin; C K Osterland
Journal:  Arch Neurol       Date:  1976-09

5.  Partial characterization of the Purkinje cell antigens in paraneoplastic cerebellar degeneration.

Authors:  J Cunningham; F Graus; N Anderson; J B Posner
Journal:  Neurology       Date:  1986-09       Impact factor: 9.910

6.  Autoimmune response of patients with paraneoplastic cerebellar degeneration to a Purkinje cell cytoplasmic protein antigen.

Authors:  K A Jaeckle; F Graus; A Houghton; C Cardon-Cardo; S L Nielsen; J B Posner
Journal:  Ann Neurol       Date:  1985-11       Impact factor: 10.422

7.  Cerebellar cortical degeneration with ovarian carcinoma.

Authors:  M M Steven; I R Mackay; P R Carnegie; P S Bhathal; R M Anderson
Journal:  Postgrad Med J       Date:  1982-01       Impact factor: 2.401

8.  Antibodies to cerebellar Purkinje cells in patients with paraneoplastic cerebellar degeneration and ovarian carcinoma.

Authors:  J E Greenlee; H R Brashear
Journal:  Ann Neurol       Date:  1983-12       Impact factor: 10.422

9.  Cerebellar dysfunction in patients with bronchogenic carcinoma: clinical and posturographic findings.

Authors:  K Wessel; H C Diener; J Dichgans; A Thron
Journal:  J Neurol       Date:  1988-05       Impact factor: 4.849
  9 in total
  3 in total

1.  Anti-Purkinje cell antibodies are specific for small-cell lung cancer but not for paraneoplastic neurological disorders.

Authors:  W Grisold; M Drlicek; U Liszka; W Popp
Journal:  J Neurol       Date:  1989-01       Impact factor: 4.849

2.  Protein kinase Cgamma autoimmunity in paraneoplastic cerebellar degeneration and non-small-cell lung cancer.

Authors:  L Sabater; L Bataller; A F Carpentier; M L Aguirre-Cruz; A Saiz; B Benyahia; J Dalmau; F Graus
Journal:  J Neurol Neurosurg Psychiatry       Date:  2006-06-26       Impact factor: 10.154

3.  Circulating antineuronal antibodies reach neurons in vivo: an autopsy study.

Authors:  M Drlicek; U Liszka; K Jellinger; A Mohn-Staudner; F Lintner; W Grisold
Journal:  J Neurol       Date:  1992-08       Impact factor: 4.849
  3 in total

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