| Literature DB >> 33852824 |
Jianjun Wu1, Nan Yan2.
Abstract
Adaptive immune cells are usually not equipped with pattern recognition receptors. In this issue of Immunity, Wang et al. revealed an "innate-like" cytosolic DNA-sensing mechanism by the KU complex in aged CD4+ T cells, which exacerbates aging-related autoimmunity.Entities:
Year: 2021 PMID： 33852824 DOI： 10.1016/j.immuni.2021.03.017
Source DB: PubMed Journal: Immunity ISSN： 1074-7613 Impact factor: 31.745