Literature DB >> 33852647

Correction: Sustained functional benefits after a single set of injections with abobotulinumtoxinA using a 2-mL injection volume in adults with cervical dystonia: 12-week results from a randomized, double-blind, placebo-controlled phase 3b study.

Atul T Patel, Mark F Lew, Khashayar Dashtipour, Stuart Isaacson, Robert A Hauser, William Ondo, Pascal Maisonobe, Stefan Wietek, Bruce Rubin, Allison Brashear.   

Abstract

[This corrects the article DOI: 10.1371/journal.pone.0245827.].

Entities:  

Year:  2021        PMID: 33852647      PMCID: PMC8046252          DOI: 10.1371/journal.pone.0250475

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


In Fig 2, the delta and p-value are missing for the last available post-baseline assessment. The missing information reflects a statistically significant difference in the mean TWSTRS total score of aboBoNT-A vs placebo at the last available data point. Please see the correct Fig 2 here.
Fig 2

Mean TWSTRS total score.

aboBoNT-A = abobotulinumtoxinA; ITT = intent-to-treat (all randomized patients); last available* = last available post-baseline (end of study or early withdrawal); TWSTRS = Toronto Western Spasmodic Torticollis Rating Scale; Δ = weighted overall treatment difference. Error lines indicate standard deviation. *Last available = last available post-baseline (end of study or early withdrawal), mean (SD) study drug exposure: 62.6 (37.8) days.

Mean TWSTRS total score.

aboBoNT-A = abobotulinumtoxinA; ITT = intent-to-treat (all randomized patients); last available* = last available post-baseline (end of study or early withdrawal); TWSTRS = Toronto Western Spasmodic Torticollis Rating Scale; Δ = weighted overall treatment difference. Error lines indicate standard deviation. *Last available = last available post-baseline (end of study or early withdrawal), mean (SD) study drug exposure: 62.6 (37.8) days.
  1 in total

1.  Sustained functional benefits after a single set of injections with abobotulinumtoxinA using a 2-mL injection volume in adults with cervical dystonia: 12-week results from a randomized, double-blind, placebo-controlled phase 3b study.

Authors:  Atul T Patel; Mark F Lew; Khashayar Dashtipour; Stuart Isaacson; Robert A Hauser; William Ondo; Pascal Maisonobe; Stefan Wietek; Bruce Rubin; Allison Brashear
Journal:  PLoS One       Date:  2021-02-01       Impact factor: 3.240

  1 in total

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