Marie Blanquet1,2,3, Guillaume Ducher4, Anaïs Sauvage5, Sylvain Dadet6, Vincent Guiyedi7, Nicolas Farigon8, Candy Guiguet-Auclair9,10, Pauline Berland9, Jérôme Bohatier11, Yves Boirie8,12, Laurent Gerbaud9,10. 1. Service de Médecine, Centre Hospitalier de MAURIAC, Mauriac, France. mblanquet@chu-clermontferrand.fr. 2. Service de Santé Publique, Centre Hospitalo-Universitaire de CLERMONT-FERRAND, Clermont-Ferrand, France. mblanquet@chu-clermontferrand.fr. 3. Université Clermont Auvergne, CHU Clermont-Ferrand, CNRS, SIGMA Clermont, Institut Pascal, F-63000, CLERMONT-FERRAND, France. mblanquet@chu-clermontferrand.fr. 4. Service de Gériatrie, BEAUMONT, Beaumont, France. 5. Diététicienne R&D-Chef de projet NutriSeniors. NUTRISET, Hameau du Bois Ricard - CS 80035 - 76770, MALAUNAY, France. 6. Service de Médecine, Centre Hospitalier de BRIOUDE, Brioude, France. 7. Service de Médecine, Centre Hospitalier de MAURIAC, Mauriac, France. 8. Service de Nutrition Clinique, Centre Hospitalo-Universitaire de CLERMONT-FERRAND, Clermont-Ferrand, France. 9. Service de Santé Publique, Centre Hospitalo-Universitaire de CLERMONT-FERRAND, Clermont-Ferrand, France. 10. Université Clermont Auvergne, CHU Clermont-Ferrand, CNRS, SIGMA Clermont, Institut Pascal, F-63000, CLERMONT-FERRAND, France. 11. Service de Gériatrie, Centre Hospitalier de Riom, RIOM, France. 12. Université Clermont Auvergne, INRA, UMR 1019, Unité de Nutrition Humaine, CLERMONT-FERRAND, France.
Abstract
BACKGROUND/ OBJECTIVES: Sarcopenia is an age-related muscle disease associated with higher mortality, morbidity risk and health costs. An easy and convenient sarcopenia screening test would be hugely valuable for clinical critical care. The study aimed to assess handgrip strength (HGS) as a screening tool for sarcopenia in acute care-unit inpatients, using the EWGSOP 1 reference-standard definition. SUBJECTS/ METHODS: Inpatients, aged 75 years old or above, of two acute care wards-a multidisciplinary care unit (MCU) and a geriatric care unit (GCU), were included between September 2017 and June 2018 in a cross-sectional study. HGS, sarcopenia, nutritional status, functional status, number of medications and sociodemographic data were collected. The accuracy of HGS as a screening test for sarcopenia was assessed by gender using receiver operating characteristic (ROC) curves and area under the curve (AUC) in a population of older patients (n = 223; age: 85.8 yrs; BMI: 26.7 kg/m²). RESULTS: Screening was positive (patients confirmed with sarcopenia by the HGS test) with cut-off values of 18 kg for women and 25.5 kg for men, with ROC analysis giving a sensitivity of 92.9% in women and 78.6% in men. ROC curve analysis found also that HGS should be strictly higher than 15 kg in women and 18 kg in men to maximise AUC. Prevalence of sarcopenia according to the EWGSOP1 definition was 31.8% (95% CI: 22.1-41.6%) in the MCU and 27.8% (95% CI: 19.6-36.0%) in the GCU. CONCLUSIONS: Acute care wards can use HGS as a valid, easy tool for early screening of sarcopenia.
BACKGROUND/ OBJECTIVES: Sarcopenia is an age-related muscle disease associated with higher mortality, morbidity risk and health costs. An easy and convenient sarcopenia screening test would be hugely valuable for clinical critical care. The study aimed to assess handgrip strength (HGS) as a screening tool for sarcopenia in acute care-unit inpatients, using the EWGSOP 1 reference-standard definition. SUBJECTS/ METHODS: Inpatients, aged 75 years old or above, of two acute care wards-a multidisciplinary care unit (MCU) and a geriatric care unit (GCU), were included between September 2017 and June 2018 in a cross-sectional study. HGS, sarcopenia, nutritional status, functional status, number of medications and sociodemographic data were collected. The accuracy of HGS as a screening test for sarcopenia was assessed by gender using receiver operating characteristic (ROC) curves and area under the curve (AUC) in a population of older patients (n = 223; age: 85.8 yrs; BMI: 26.7 kg/m²). RESULTS: Screening was positive (patients confirmed with sarcopenia by the HGS test) with cut-off values of 18 kg for women and 25.5 kg for men, with ROC analysis giving a sensitivity of 92.9% in women and 78.6% in men. ROC curve analysis found also that HGS should be strictly higher than 15 kg in women and 18 kg in men to maximise AUC. Prevalence of sarcopenia according to the EWGSOP1 definition was 31.8% (95% CI: 22.1-41.6%) in the MCU and 27.8% (95% CI: 19.6-36.0%) in the GCU. CONCLUSIONS: Acute care wards can use HGS as a valid, easy tool for early screening of sarcopenia.
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