Li Luo1,2,3,4, Huan Zeng1,2,3, Mao Zeng1,2,3, Xueqing Liu1, Xianglong Xu1,2,3,4,5, Lianlian Wang6,7,8,9, Yong Zhao10,11,12. 1. School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, China. 2. Research Center for Medicine and Social Development, Chongqing Medical University, Chongqing, 400016, China. 3. Collaborative Innovation Center of Social Risks Governance in Health, Chongqing Medical University, Chongqing, 400016, China. 4. Chengdu Center for Disease Control and Prevention, 610041, Chengdu, China. 5. Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, 3800, Melbourne, Australia. 6. Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, 3800, Melbourne, Australia. llian_w@163.com. 7. The Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, 400016, Chongqing, China. llian_w@163.com. 8. Department of Reproduction Health and Infertility, The First Affiliated Hospital of Chongqing Medical University, 400016, Chongqing, China. llian_w@163.com. 9. Canada-China-New Zealand Joint Laboratory of Maternal and Fetal Medicine, Chongqing Medical University, 400016, Chongqing, China. llian_w@163.com. 10. School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, China. zhaoyong@cqmu.edu.cn. 11. Research Center for Medicine and Social Development, Chongqing Medical University, Chongqing, 400016, China. zhaoyong@cqmu.edu.cn. 12. Collaborative Innovation Center of Social Risks Governance in Health, Chongqing Medical University, Chongqing, 400016, China. zhaoyong@cqmu.edu.cn.
Abstract
BACKGROUND: After the implementation of the universal two-child policy in China, the increase in parity has led to an increase in adverse pregnancy outcomes. The impact of one and two fetuses on the incidence of fetal macrosomia has not been fully confirmed in China. This study aimed to explore the differences in the incidence of fetal macrosomia in first and second pregnancies in Western China after the implementation of the universal two-child policy. METHODS: A total of 1598 pregnant women from three hospitals were investigated by means of a cross-sectional study from August 2017 to January 2018. Participants were recruited by convenience and divided into first and second pregnancy groups. These groups included 1094 primiparas and 504 women giving birth to their second child. Univariate and multivariate logistic regression analyses were performed to discuss the differences in the incidence of fetal macrosomia in first and second pregnancies. RESULTS: No significant difference was found in the incidence of macrosomia in the first pregnancy group (7.2%) and the second pregnancy group (7.1%). In the second-time pregnant mothers, no significant association was found between the macrosomia of the second child (5.5%) and that of the first child (4.7%). The multivariate logistic regression model showed that mothers older than 30 years are not likely to give birth to children with macrosomia (odds ratio (OR) 0.6, 95% confidence interval (CI) 0.4,0.9). CONCLUSIONS: The incidence of macrosomia in Western China is might not be affected by the birth of the second child and is not increased by low parity.
BACKGROUND: After the implementation of the universal two-child policy in China, the increase in parity has led to an increase in adverse pregnancy outcomes. The impact of one and two fetuses on the incidence of fetal macrosomia has not been fully confirmed in China. This study aimed to explore the differences in the incidence of fetal macrosomia in first and second pregnancies in Western China after the implementation of the universal two-child policy. METHODS: A total of 1598 pregnant women from three hospitals were investigated by means of a cross-sectional study from August 2017 to January 2018. Participants were recruited by convenience and divided into first and second pregnancy groups. These groups included 1094 primiparas and 504 women giving birth to their second child. Univariate and multivariate logistic regression analyses were performed to discuss the differences in the incidence of fetal macrosomia in first and second pregnancies. RESULTS: No significant difference was found in the incidence of macrosomia in the first pregnancy group (7.2%) and the second pregnancy group (7.1%). In the second-time pregnant mothers, no significant association was found between the macrosomia of the second child (5.5%) and that of the first child (4.7%). The multivariate logistic regression model showed that mothers older than 30 years are not likely to give birth to children with macrosomia (odds ratio (OR) 0.6, 95% confidence interval (CI) 0.4,0.9). CONCLUSIONS: The incidence of macrosomia in Western China is might not be affected by the birth of the second child and is not increased by low parity.
Authors: Ai Koyanagi; Jun Zhang; Amarjargal Dagvadorj; Fumi Hirayama; Kenji Shibuya; João Paulo Souza; Ahmet Metin Gülmezoglu Journal: Lancet Date: 2013-01-04 Impact factor: 79.321