Literature DB >> 33847374

Identification and analysis of genes associated with lung adenocarcinoma by integrated bioinformatics methods.

Hui Xie1,2, Jian-Fang Zhang3, Qing Li2,4.   

Abstract

Lung adenocarcinoma (LUAD) is one of the most common forms of lung cancer, with a very high mortality rate. Although the treatments available for LUAD have become more effective in recent years, significant improvement is still needed. Advances in sequencing technologies and bioinformatics analysis have enabled new approaches to be developed for identifying drug targets. In this work we utilized data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases to identify hub genes related to LUAD through Weighted Gene Correlation Network Analysis (WGCNA) and other bioinformatics methods, with the goal of identifying new drug targets for cancer treatment.
© 2021 John Wiley & Sons Ltd/University College London.

Entities:  

Keywords:  RXFP1; bioinformatics; lung adenocarcinoma; weighted gene correlation network analysis

Year:  2021        PMID: 33847374     DOI: 10.1111/ahg.12418

Source DB:  PubMed          Journal:  Ann Hum Genet        ISSN: 0003-4800            Impact factor:   1.670


  2 in total

1.  Constructing a Prognostic Gene Signature for Lung Adenocarcinoma Based on Weighted Gene Co-Expression Network Analysis and Single-Cell Analysis.

Authors:  Biqian Fu; Lin Lu; Haifu Huang
Journal:  Int J Gen Med       Date:  2022-06-03

2.  Exploration of the Potential Link, Hub Genes, and Potential Drugs for Coronavirus Disease 2019 and Lung Cancer Based on Bioinformatics Analysis.

Authors:  Ye Wang; Qing Li; Jianfang Zhang; Hui Xie
Journal:  J Oncol       Date:  2022-09-26       Impact factor: 4.501

  2 in total

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