Literature DB >> 3384441

The AKT1 proto-oncogene maps to human chromosome 14, band q32.

S P Staal1, K Huebner, C M Croce, N Z Parsa, J R Testa.   

Abstract

The human AKT1 gene is the proto-oncogene of the viral oncogene v-akt. The AKT1 gene has been localized to human chromosome 14, band q32, proximal to the heavy-chain immunoglobulin locus (IGHM), by analysis of human-hamster somatic cell hybrids and by in situ hybridization. Chromosome rearrangements of this band which occur in T-lymphoid malignancies and Hodgkin's disease may affect the AKT1 gene.

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Year:  1988        PMID： 3384441     DOI： 10.1016/0888-7543(88)90114-0

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  16 in total

Review 1.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 2.  Mouse chromosome 12.

Authors:  P D'Eustachio
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 3.  The Src homology 2 domain tyrosine phosphatases SHP-1 and SHP-2: diversified control of cell growth, inflammation, and injury.

Authors:  Z Z Chong; K Maiese
Journal:  Histol Histopathol       Date:  2007-11       Impact factor: 2.303

Review 4.  Mouse chromosome 12.

Authors:  P D'Eustachio
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 5.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

6.  A linkage map of distal mouse chromosome 12.

Authors:  M Cho; V Villani; P D'Eustachio
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 7.  Oxidative stress biology and cell injury during type 1 and type 2 diabetes mellitus.

Authors:  Kenneth Maiese; Simona Daniela Morhan; Zhao Zhong Chong
Journal:  Curr Neurovasc Res       Date:  2007-02       Impact factor: 1.990

8.  Non-peptidic substrate-mimetic inhibitors of Akt as potential anti-cancer agents.

Authors:  Katherine J Kayser-Bricker; Matthew P Glenn; Sang Hoon Lee; Said M Sebti; Jin Q Cheng; Andrew D Hamilton
Journal:  Bioorg Med Chem       Date:  2008-09-27       Impact factor: 3.641

Review 9.  Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

Authors:  P J Coffer; J Jin; J R Woodgett
Journal:  Biochem J       Date:  1998-10-01       Impact factor: 3.857

Review 10.  Mechanistic insights into diabetes mellitus and oxidative stress.

Authors:  Kenneth Maiese; Zhao Zhong Chong; Yan Chen Shang
Journal:  Curr Med Chem       Date:  2007       Impact factor: 4.530
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