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Literature DB >> 338442

Carcinoembryonic antigen (CEA) in the normal human small intestine: a light and electron microscopic study.

Abstract

An immunoperoxidase method for the demonstration of carcinoembryonic antigen (CEA) in tissues was applied to formalin-fixed paraffin embedded and glutaraldehyde-fixed resin sections of normal human small intestine. CEA could easily be demonstrated coating the surface of the small intestine, lining the crypts, and in goblet cells, indicating its presence there in considerable concentration. At the ultrastructural level CEA was localised in the glycocalyx and in mucin granules of goblet cells but not intracytoplasmically.

Entities: Chemical Gene Species

Mesh：

Substances：
Carcinoembryonic Antigen

Year: 1977 PMID： 338442 PMCID： PMC1411697 DOI： 10.1136/gut.18.10.786

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

20 in total

1. Immunohistological localization of carcinoembryonic antigen and nonspecific cross-reacting antigen in gastrointestinal normal and tumoral tissues.

Authors: P Burtin; S von Kleist; M C Sabine; M King
Journal: Cancer Res Date: 1973-12 Impact factor: 12.701

2. Carcinoembryonic antigen in medullary carcinoma of thyroid.

Authors: P Isaacson; M A Judd
Journal: Lancet Date: 1976-11-06 Impact factor: 79.321

3. Carcinoembryonic antigen(s) in liver disease. II. Isolation from human cirrhotic liver and serum and from normal liver.

Authors: H Z Kupchik; N Zamcheck
Journal: Gastroenterology Date: 1972-07 Impact factor: 22.682

4. Tissue demonstration of carcinoembryonic antigen (CEA) in ulcerative colitis.

Authors: P Isaacson
Journal: Gut Date: 1976-07 Impact factor: 23.059

5. Carcinoembryonic antigen in histopathology: immunoperoxidase staining of conventional tissue sections.

Authors: D M Goldenberg; R M Sharkey; F J Primus
Journal: J Natl Cancer Inst Date: 1976-07 Impact factor: 13.506

6. Carcinoembryonic antigen (CEA) in feces and plasma of normal subjects and patients with colorectal carcinoma.

Authors: E G Elias; E D Holyoke; T M Chu
Journal: Dis Colon Rectum Date: 1974 Jan-Feb Impact factor: 4.585

7. Carcinoembryonic antigen (CEA) in non digestive cancerous and normal tissues.

Authors: G Pusztaszeri; J P Mach
Journal: Immunochemistry Date: 1973-03

Review 8. Report of the workshop on the carcinoembryonic antigen (cea): the present position and proposals for future investigation.

Authors: A M Neville; D J Laurence
Journal: Int J Cancer Date: 1974-07-15 Impact factor: 7.396

9. Immunohistochemistry of carcinoembryonic antigen: characterisation of cross-reactions with other glycoproteins.

Authors: P Isaacson; M A Judd
Journal: Gut Date: 1977-10 Impact factor: 23.059

10. A simple method for removing the resin from epoxy-embedded tissue.

Authors: H D MAYOR; J C HAMPTON; B ROSARIO
Journal: J Biophys Biochem Cytol Date: 1961-04

4 in total

1. Purification of human intestinal goblet cell antigen (GOA), its immunohistological demonstration in the intestine and in mucus producing gastrointestinal adenocarcinomas.

Authors: W Rapp; M Windisch; P Peschke; K Wurster
Journal: Virchows Arch A Pathol Anat Histol Date: 1979-05-31