Literature DB >> 33842119

Helminthic Infection in the Background of Active Pulmonary Tuberculosis: An Underreported Co-infection.

Arshi Syal1, Yajur Arya1, Nikita N Hapani1, Monica Gupta1, Saurabh Gaba1.   

Abstract

Helminthic infections are widely prevalent in resource-poor countries. Tuberculosis, a disease contributing significantly to morbidity and mortality in endemic areas, often co-exists with helminthic infections. Poor living standards predispose to both of them. Moreover, untreated helminthic infection enhances the deleterious impact of tuberculosis, largely through immunological alteration. We are reporting the case of a 22-year-old male who presented with a month-long history of abdominal pain, nausea, vomiting, fever and cough complicated by hemoptysis, along with an episode of the passage of a worm in the vomitus. A thorough workup revealed active pulmonary tuberculosis co-existing with intestinal ascariasis. Anti-helminthic therapy was initiated along with anti-tubercular therapy, leading to significant improvement.
Copyright © 2021, Syal et al.

Entities:  

Keywords:  ascariasis; helminths; mebendazole; pulmonary; tuberculosis

Year:  2021        PMID: 33842119      PMCID: PMC8022635          DOI: 10.7759/cureus.13741

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  15 in total

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Journal:  Vaccine       Date:  2005-02-03       Impact factor: 3.641

4.  Anthelmintic Therapy Modifies the Systemic and Mycobacterial Antigen-Stimulated Cytokine Profile in Helminth-Latent Mycobacterium tuberculosis Coinfection.

Authors:  Rajamanickam Anuradha; Saravanan Munisankar; Yukthi Bhootra; Chandrakumar Dolla; Paul Kumaran; Thomas B Nutman; Subash Babu
Journal:  Infect Immun       Date:  2017-03-23       Impact factor: 3.441

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Review 6.  Th2 cytokines in susceptibility to tuberculosis.

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Journal:  Curr Mol Med       Date:  2007-05       Impact factor: 2.222

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Authors:  Getaneh Alemu; Mohammedaman Mama
Journal:  BMC Infect Dis       Date:  2017-01-13       Impact factor: 3.090

Review 8.  Interactions between helminths and tuberculosis infections: Implications for tuberculosis diagnosis and vaccination in Africa.

Authors:  Simeon I Cadmus; Victor O Akinseye; Babafemi O Taiwo; Elena O Pinelli; Dick van Soolingen; Shelley G Rhodes
Journal:  PLoS Negl Trop Dis       Date:  2020-06-04

9.  Anthelmintic drugs for treating ascariasis.

Authors:  Lucieni O Conterno; Marilia D Turchi; Ione Corrêa; Ricardo Augusto Monteiro de Barros Almeida
Journal:  Cochrane Database Syst Rev       Date:  2020-04-14

10.  The optimal timing of post-treatment sampling for the assessment of anthelminthic drug efficacy against Ascaris infections in humans.

Authors:  Bruno Levecke; Alice V Easton; Piet Cools; Marco Albonico; Shaali Ame; John S Gilleard; Jennifer Keiser; Antonio Montresor; Roger Prichard; Johnny Vlaminck; Jozef Vercruysse
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2018-01-13       Impact factor: 4.077

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