Lente L Kroon1,2,3, Janneke van Roij1,4,5,6, Ida J Korfage7, An K L Reyners8, Marieke H J van den Beuken-van Everdingen9, Marien O den Boer10, Geert-Jan Creemers11, Alexander de Graeff12, Mathijs P Hendiks13, Jarmo C B Hunting14, Wouter K de Jong15, Evelien J M Kuip16, Hanneke W M van Laarhoven17, Lobke van Leeuwen18, Anne S R van Lindert19, Caroline M P W Mandigers20, Peter Nieboer21, Annemieke van der Padt-Pruijsten22, Tineke J Smilde23, Dirkje W Sommeijer17,24, Martine F Thijs25, Marian A Tiemessen26, Allert H Vos27, Art Vreugdenhil28, Philo T Werner29, Lia van Zuylen30,31, Lonneke V van de Poll-Franse1,4,32, Natasja J H Raijmakers33,34. 1. Department of Research & Development, Netherlands Comprehensive Cancer Organization (IKNL), PO box 19079, 3501 DB, Utrecht, The Netherlands. 2. University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. 3. Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. 4. Department of Medical and Clinical Psychology, CoRPS - Center of Research on Psychology in Somatic Diseases, Tilburg University, Tilburg, The Netherlands. 5. Netherlands Association for Palliative Care (PZNL), Utrecht, The Netherlands. 6. Department of Psychology, Pantein, Boxmeer, The Netherlands. 7. Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands. 8. Department of Medical Oncology, University Medical Center Groningen, Groningen, The Netherlands. 9. Center of Expertise Palliative Care, Maastricht University Medical Center, Maastricht, The Netherlands. 10. Department of Medical Oncology, Laurentius Hospital, Roermond, The Netherlands. 11. Department of Medical Oncology, Catharina Hospital, Eindhoven, The Netherlands. 12. Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands. 13. Department of Medical Oncology, Northwest Clinics, Alkmaar, The Netherlands. 14. Department of Medical Oncology, St. Antonius Hospital, Utrecht, The Netherlands. 15. Department of Pulmonology, Hospital Gelderse Vallei, Ede, The Netherlands. 16. Department of Medical Oncology, Radboud University Medical Center, Nijmegen, The Netherlands. 17. Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands. 18. Department of Medical Oncology, Diakonessenhuis, Utrecht, The Netherlands. 19. Department of Pulmonology, University Medical Center Utrecht, Utrecht, The Netherlands. 20. Department of Medical Oncology, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands. 21. Department of Medical Oncology, Wilhelmina Hospital Assen, Assen, The Netherlands. 22. Department of Internal Medicine, Maasstad Hospital, Rotterdam, The Netherlands. 23. Department of Medical Oncology, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands. 24. Department of Internal Medicine, FlevoHospital, Almere, The Netherlands. 25. Department of Medical Oncology, Ikazia Hospital, Rotterdam, The Netherlands. 26. Department of Pulmonology, Dijklander Hospital, Hoorn, The Netherlands. 27. Department of Medical Oncology, Bernhoven Hospital, Uden, The Netherlands. 28. Department of Medical Oncology, Maxima Medical Center, Eindhoven, The Netherlands. 29. Department of Medical Oncology, VieCuri Medical Center, Venlo, The Netherlands. 30. Department of Medical Oncology, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands. 31. Department of Medical Oncology, Amsterdam University Medical Centers, Amsterdam, The Netherlands. 32. Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. 33. Department of Research & Development, Netherlands Comprehensive Cancer Organization (IKNL), PO box 19079, 3501 DB, Utrecht, The Netherlands. n.raijmakers@iknl.nl. 34. Netherlands Association for Palliative Care (PZNL), Utrecht, The Netherlands. n.raijmakers@iknl.nl.
Abstract
PURPOSE: Advance Care Planning (ACP) is positively associated with the quality of care, but its impact on emotional functioning is ambiguous. This study investigated the association between perceptions of ACP involvement and emotional functioning in patients with advanced cancer. METHODS: This study analyzed baseline data of 1,001 patients of the eQuiPe study, a prospective, longitudinal, multicenter, observational study on quality of care and quality of life in patients with advanced cancer in the Netherlands. Patients with metastatic solid cancer were asked to participate between November 2017 and January 2020. Patients' perceptions of ACP involvement were measured by three self-administered statements. Emotional functioning was measured by the EORTC-QLQ-C30. A linear multivariable regression analysis was performed while taking gender, age, migrant background, education, marital status, and symptom burden into account. RESULTS: The majority of patients (87%) reported that they were as much involved as they wanted to be in decisions about their future medical treatment and care. Most patients felt that their relatives (81%) and physicians (75%) were familiar with their preferences for future medical treatment and care. A positive association was found between patients' perceptions of ACP involvement and their emotional functioning (b=0.162, p<0.001, 95%CI[0.095;0.229]) while controlling for relevant confounders. CONCLUSIONS: Perceptions of involvement in ACP are positively associated with emotional functioning in patients with advanced cancer. Future studies are needed to further investigate the effect of ACP on emotional functioning. TRIAL REGISTRATION NUMBER: NTR6584 Date of registration: 30 June 2017 IMPLICATIONS FOR CANCER SURVIVORS: Patients' emotional functioning might improve from routine discussions regarding goals of future care. Therefore, integration of ACP into palliative might be promising.
PURPOSE: Advance Care Planning (ACP) is positively associated with the quality of care, but its impact on emotional functioning is ambiguous. This study investigated the association between perceptions of ACP involvement and emotional functioning in patients with advanced cancer. METHODS: This study analyzed baseline data of 1,001 patients of the eQuiPe study, a prospective, longitudinal, multicenter, observational study on quality of care and quality of life in patients with advanced cancer in the Netherlands. Patients with metastatic solid cancer were asked to participate between November 2017 and January 2020. Patients' perceptions of ACP involvement were measured by three self-administered statements. Emotional functioning was measured by the EORTC-QLQ-C30. A linear multivariable regression analysis was performed while taking gender, age, migrant background, education, marital status, and symptom burden into account. RESULTS: The majority of patients (87%) reported that they were as much involved as they wanted to be in decisions about their future medical treatment and care. Most patients felt that their relatives (81%) and physicians (75%) were familiar with their preferences for future medical treatment and care. A positive association was found between patients' perceptions of ACP involvement and their emotional functioning (b=0.162, p<0.001, 95%CI[0.095;0.229]) while controlling for relevant confounders. CONCLUSIONS: Perceptions of involvement in ACP are positively associated with emotional functioning in patients with advanced cancer. Future studies are needed to further investigate the effect of ACP on emotional functioning. TRIAL REGISTRATION NUMBER: NTR6584 Date of registration: 30 June 2017 IMPLICATIONS FOR CANCER SURVIVORS: Patients' emotional functioning might improve from routine discussions regarding goals of future care. Therefore, integration of ACP into palliative might be promising.
Entities:
Keywords:
Advance care planning; Advanced cancer; Palliative care; Quality of life
Authors: Johannes M Giesinger; Fanny L C Loth; Neil K Aaronson; Juan I Arraras; Giovanni Caocci; Fabio Efficace; Mogens Groenvold; Marieke van Leeuwen; Morten Aa Petersen; John Ramage; Krzysztof A Tomaszewski; Teresa Young; Bernhard Holzner Journal: J Clin Epidemiol Date: 2019-10-19 Impact factor: 6.437
Authors: Lonneke V van de Poll-Franse; Nicole Horevoorts; Mies van Eenbergen; Johan Denollet; Jan Anne Roukema; Neil K Aaronson; Ad Vingerhoets; Jan Willem Coebergh; Jolanda de Vries; Marie-Louise Essink-Bot; Floortje Mols Journal: Eur J Cancer Date: 2011-05-27 Impact factor: 9.162
Authors: Judith A C Rietjens; Ida J Korfage; Lesley Dunleavy; Nancy J Preston; Lea J Jabbarian; Caroline Arnfeldt Christensen; Maja de Brito; Francesco Bulli; Glenys Caswell; Branka Červ; Johannes van Delden; Luc Deliens; Giuseppe Gorini; Mogens Groenvold; Dirk Houttekier; Francesca Ingravallo; Marijke C Kars; Urška Lunder; Guido Miccinesi; Alenka Mimić; Eugenio Paci; Sheila Payne; Suzanne Polinder; Kristian Pollock; Jane Seymour; Anja Simonič; Anna Thit Johnsen; Mariëtte N Verkissen; Esther de Vries; Andrew Wilcock; Marieke Zwakman; Agnes van der Heide Pl Journal: BMC Cancer Date: 2016-04-08 Impact factor: 4.430
Authors: Janneke van Roij; Myrte Zijlstra; Laurien Ham; Linda Brom; Heidi Fransen; Art Vreugdenhil; Natasja Raijmakers; Lonneke van de Poll-Franse Journal: BMC Palliat Care Date: 2020-09-09 Impact factor: 3.234
Authors: Karlijn de Joode; Jolien Tol; Paul Hamberg; Marissa Cloos; Elisabeth A Kastelijn; Jessica S W Borgers; Veerle J A A Nuij; Yarne Klaver; Gerarda J M Herder; Pim G N J Mutsaers; Daphne W Dumoulin; Esther Oomen-de Hoop; Nico G J van Diemen; Eduard J Libourel; Erica J Geraedts; Gerben P Bootsma; Cor H van der Leest; Anne L Peerdeman; Karin H Herbschleb; Otto J Visser; Haiko J Bloemendal; Hanneke W M van Laarhoven; Elisabeth G E de Vries; Lizza E L Hendriks; Laurens V Beerepoot; Hans M Westgeest; Franchette W P J van den Berkmortel; John B A G Haanen; Anne-Marie C Dingemans; Astrid A M van der Veldt Journal: Eur J Cancer Date: 2021-10-25 Impact factor: 9.162