Literature DB >> 3383820

Prostatic carcinogenesis evoked by cellular interaction.

L W Chung1, S M Chang, C Bell, H Zhau, J Y Ro, A C von Eschenbach.   

Abstract

Inoculation of tumorigenic prostatic stroma and nontumorigenic prostatic epithelia into the subcutaneous space of syngeneic rats induced the development of carcinosarcoma. The induced tumors, which were composed of a mixture of adenocarcinoma and fibrosarcoma, were androgen responsive. This model offers a novel mechanism for prostatic carcinogenesis in which prostatic fibroblasts determine epithelial growth, androgen responsiveness, and tumorigenicity. Our results emphasize the potential importance of an epigenetic pathway in prostatic carcinogenesis.

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Year:  1988        PMID： 3383820      PMCID： PMC1474533          DOI： 10.1289/ehp.887723

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN： 0091-6765            Impact factor:   9.031


  24 in total

1.  Tissue interaction in androgen response of embryonic mammary rudiment of mouse: identification of target tissue for testosterone.

Authors:  K Kratochwil; P Schwartz
Journal:  Proc Natl Acad Sci U S A       Date:  1976-11       Impact factor: 11.205

Review 2.  Mechanisms of organogenetic tissue interaction.

Authors:  C Grobstein
Journal:  Natl Cancer Inst Monogr       Date:  1967-09

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Authors:  A V Roy; M E Brower; J E Hayden
Journal:  Clin Chem       Date:  1971-11       Impact factor: 8.327

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Authors:  H Harris; O J Miller; G Klein; P Worst; T Tachibana
Journal:  Nature       Date:  1969-07-26       Impact factor: 49.962

5.  Carcinosarcoma of the prostate with metastasis of both elements: case report.

Authors:  J R Haddad; E C Reyes
Journal:  J Urol       Date:  1970-01       Impact factor: 7.450

Review 6.  Estrogenic regulation of growth and polypeptide growth factor secretion in human breast carcinoma.

Authors:  R B Dickson; M E Lippman
Journal:  Endocr Rev       Date:  1987-02       Impact factor: 19.871

7.  Growth responses of normal, benign hyperplastic, and malignant human prostatic epithelial cells in vitro to cholera toxin, pituitary extract, and hydrocortisone.

Authors:  D M Peehl; T A Stamey
Journal:  Prostate       Date:  1986       Impact factor: 4.104

8.  Purification and partial characterization of prostate-derived growth factor.

Authors:  S Maehama; D Li; H Nanri; J F Leykam; T F Deuel
Journal:  Proc Natl Acad Sci U S A       Date:  1986-11       Impact factor: 11.205

9.  Amino-terminal sequence of a large form of basic fibroblast growth factor isolated from human benign prostatic hyperplastic tissue.

Authors:  M T Story; F Esch; S Shimasaki; J Sasse; S C Jacobs; R K Lawson
Journal:  Biochem Biophys Res Commun       Date:  1987-02-13       Impact factor: 3.575

10.  Glycosaminoglycan synthesis by embryonic inductors: neural tube, notochord, and lens.

Authors:  E D Hay; S Meier
Journal:  J Cell Biol       Date:  1974-09       Impact factor: 10.539
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  4 in total

1.  Fibroblast-mediated acceleration of human epithelial tumor growth in vivo.

Authors:  J L Camps; S M Chang; T C Hsu; M R Freeman; S J Hong; H E Zhau; A C von Eschenbach; L W Chung
Journal:  Proc Natl Acad Sci U S A       Date:  1990-01       Impact factor: 11.205

Review 2.  Changes in extracellular matrix (ECM) and ECM-associated proteins in the metastatic progression of prostate cancer.

Authors:  Delisha A Stewart; Carlton R Cooper; Robert A Sikes
Journal:  Reprod Biol Endocrinol       Date:  2004-01-07       Impact factor: 5.211

Review 3.  Tumor and the microenvironment: a chance to reframe the paradigm of carcinogenesis?

Authors:  Mariano Bizzarri; Alessandra Cucina
Journal:  Biomed Res Int       Date:  2014-06-12       Impact factor: 3.411

4.  Fatty acid activated PPARγ promotes tumorigenicity of prostate cancer cells by up regulating VEGF via PPAR responsive elements of the promoter.

Authors:  Farzad S Forootan; Shiva S Forootan; Xiaojun Gou; Jin Yang; Bichong Liu; Danqing Chen; Majed Saad Al Fayi; Waseem Al-Jameel; Philip S Rudland; Syed A Hussain; Youqiang Ke
Journal:  Oncotarget       Date:  2016-02-23
  4 in total

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