Literature DB >> 33837754

Role of genetics in atrial fibrillation management.

Michiel Rienstra1, Joylene E Siland1, Patrick T Ellinor2,3,4.   

Abstract

Atrial fibrillation (AF) management has significantly improved during the career of professor Crijns. Research was implemented into guidelines and clinical practice. However, despite advances in AF management, large differences between individual treatment responses still exist and the mechanisms underlying initiation and perpetuation of AF are not completely understood. International collaborations have revealed the genetic contribution to AF and steps towards improving AF management are being made. In this short review, the most important paradigms shifts in the field of AF genetics are recognized and the future role of genetics in personalized management of AF is discussed. Published on behalf of the European Society of Cardiology. All rights reserved.
© The Author(s) 2021. For permissions, please email: journals.permissions@oup.com.

Entities:  

Keywords:  Atrial fibrillation; Genetics; Risk factors; Treatment

Mesh：

Year:  2021        PMID： 33837754      PMCID： PMC8035706          DOI： 10.1093/europace/euaa366

Source DB:  PubMed          Journal:  Europace        ISSN： 1099-5129            Impact factor:   5.214


  33 in total

Review 1.  A New Therapeutic Framework for Atrial Fibrillation Drug Development.

Authors:  Saptarsi M Haldar; Jörg Hüser; Yen-Sin Ang; Sridharan Rajamani
Journal:  Circ Res       Date:  2020-06-18       Impact factor: 17.367

2.  Large-scale whole-genome sequencing of the Icelandic population.

Authors:  Daniel F Gudbjartsson; Hannes Helgason; Sigurjon A Gudjonsson; Florian Zink; Asmundur Oddson; Arnaldur Gylfason; Soren Besenbacher; Gisli Magnusson; Bjarni V Halldorsson; Eirikur Hjartarson; Gunnar Th Sigurdsson; Simon N Stacey; Michael L Frigge; Hilma Holm; Jona Saemundsdottir; Hafdis Th Helgadottir; Hrefna Johannsdottir; Gunnlaugur Sigfusson; Gudmundur Thorgeirsson; Jon Th Sverrisson; Solveig Gretarsdottir; G Bragi Walters; Thorunn Rafnar; Bjarni Thjodleifsson; Einar S Bjornsson; Sigurdur Olafsson; Hildur Thorarinsdottir; Thora Steingrimsdottir; Thora S Gudmundsdottir; Asgeir Theodors; Jon G Jonasson; Asgeir Sigurdsson; Gyda Bjornsdottir; Jon J Jonsson; Olafur Thorarensen; Petur Ludvigsson; Hakon Gudbjartsson; Gudmundur I Eyjolfsson; Olof Sigurdardottir; Isleifur Olafsson; David O Arnar; Olafur Th Magnusson; Augustine Kong; Gisli Masson; Unnur Thorsteinsdottir; Agnar Helgason; Patrick Sulem; Kari Stefansson
Journal:  Nat Genet       Date:  2015-03-25       Impact factor: 38.330

3.  Familial aggregation of atrial fibrillation in Iceland.

Authors:  David O Arnar; Sverrir Thorvaldsson; Teri A Manolio; Gudmundur Thorgeirsson; Kristleifur Kristjansson; Hakon Hakonarson; Kari Stefansson
Journal:  Eur Heart J       Date:  2006-01-20       Impact factor: 29.983

4.  Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysis.

Authors:  Jessica L Mega; Sandra L Close; Stephen D Wiviott; Lei Shen; Joseph R Walker; Tabassome Simon; Elliott M Antman; Eugene Braunwald; Marc S Sabatine
Journal:  Lancet       Date:  2010-10-16       Impact factor: 79.321

5.  Familial aggregation of atrial fibrillation: a study in Danish twins.

Authors:  Ingrid Elisabeth Christophersen; Lasse Steen Ravn; Esben Budtz-Joergensen; Axel Skytthe; Stig Haunsoe; Jesper Hastrup Svendsen; Kaare Christensen
Journal:  Circ Arrhythm Electrophysiol       Date:  2009-04-23

6.  KCNQ1 gain-of-function mutation in familial atrial fibrillation.

Authors:  Yi-Han Chen; Shi-Jie Xu; Said Bendahhou; Xiao-Liang Wang; Ying Wang; Wen-Yuan Xu; Hong-Wei Jin; Hao Sun; Xiao-Yan Su; Qi-Nan Zhuang; Yi-Qing Yang; Yue-Bin Li; Yi Liu; Hong-Ju Xu; Xiao-Fei Li; Ning Ma; Chun-Ping Mou; Zhu Chen; Jacques Barhanin; Wei Huang
Journal:  Science       Date:  2003-01-10       Impact factor: 47.728

7.  Genetic Risk Prediction of Atrial Fibrillation.

Authors:  Steven A Lubitz; Xiaoyan Yin; Henry J Lin; Matthew Kolek; J Gustav Smith; Stella Trompet; Michiel Rienstra; Natalia S Rost; Pedro L Teixeira; Peter Almgren; Christopher D Anderson; Lin Y Chen; Gunnar Engström; Ian Ford; Karen L Furie; Xiuqing Guo; Martin G Larson; Kathryn L Lunetta; Peter W Macfarlane; Bruce M Psaty; Elsayed Z Soliman; Nona Sotoodehnia; David J Stott; Kent D Taylor; Lu-Chen Weng; Jie Yao; Bastiaan Geelhoed; Niek Verweij; Joylene E Siland; Sekar Kathiresan; Carolina Roselli; Dan M Roden; Pim van der Harst; Dawood Darbar; J Wouter Jukema; Olle Melander; Jonathan Rosand; Jerome I Rotter; Susan R Heckbert; Patrick T Ellinor; Alvaro Alonso; Emelia J Benjamin
Journal:  Circulation       Date:  2016-10-28       Impact factor: 39.918

8.  Dysfunction of Myosin Light-Chain 4 (MYL4) Leads to Heritable Atrial Cardiomyopathy With Electrical, Contractile, and Structural Components: Evidence From Genetically-Engineered Rats.

Authors:  Wenhui Peng; Miaoxin Li; Hailing Li; Kai Tang; Jianhui Zhuang; Jianguo Zhang; Jingjing Xiao; Hui Jiang; Dali Li; Yongchun Yu; Pak C Sham; Stanley Nattel; Yawei Xu
Journal:  J Am Heart Assoc       Date:  2017-10-28       Impact factor: 5.501

Review 9.  Epigenetic and Transcriptional Networks Underlying Atrial Fibrillation.

Authors:  Antoinette F van Ouwerkerk; Amelia W Hall; Zachary A Kadow; Sonja Lazarevic; Jasmeet S Reyat; Nathan R Tucker; Rangarajan D Nadadur; Fernanda M Bosada; Valerio Bianchi; Patrick T Ellinor; Larissa Fabritz; James F Martin; Wouter de Laat; Paulus Kirchhof; Ivan P Moskowitz; Vincent M Christoffels
Journal:  Circ Res       Date:  2020-06-18       Impact factor: 17.367

10.  Imputation-based genomic coverage assessments of current human genotyping arrays.

Authors:  Sarah C Nelson; Kimberly F Doheny; Elizabeth W Pugh; Jane M Romm; Hua Ling; Cecelia A Laurie; Sharon R Browning; Bruce S Weir; Cathy C Laurie
Journal:  G3 (Bethesda)       Date:  2013-10-03       Impact factor: 3.154
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