| Literature DB >> 33834270 |
Kentaro Iwata1,2, Takeshi Kitai3,4, Yoshihiro Yoshimura5, Akihiro Honda1, Takayuki Shimogai1, Shuto Otsuka1, Ryuya Takimoto1, Kanji Yamada1,2, Yutaka Furukawa6, Nobuo Kohara1, Akira Ishikawa2.
Abstract
Activities of daily living (ADL) are important prognostic factors for heart failure. The functional independent measure (FIM) has emerged as a comprehensive valid measure of ADL from both physical and cognitive perspectives. This study aimed to investigate the prognostic impact of the FIM score on clinical outcomes in hospitalized patients with acute decompensated heart failure (ADHF). We retrospectively analyzed 473 ADHF patients, with available pre-discharge FIM scores, admitted to our institution between May 2018 and May 2020. Primary outcome measures, defined as a composite of 180-day all-cause deaths and readmissions, were compared among three tertiles. The median FIM score was 102 (interquartile range: 85-115). Tertile 1 corresponded to an FIM score > 111 (n = 154), Tertile 2 to that of 90-111 (n = 167), and Tertile 3 to that of < 90 (n = 152). During follow-up, 28 deaths and 114 readmissions occurred. Patients with lower FIM scores were associated with a graded increase in the risk of primary outcome measure (p = 0.001). Even after multivariable adjustment, the results remained significant [Tertile 1 vs 3; adjusted hazard ratio: 3.28 (95% confidence interval: 1.72-6.56), p < 0.001; Tertile 2 vs 3; 2.32 (1.27-4.47), p = 0.006]. FIM scores were significantly associated with readmission or death within 180 days of discharge in hospitalized ADHF patients.Entities:
Keywords: Activities of daily living; Elderly; Frailty; Heart failure
Mesh:
Year: 2021 PMID: 33834270 DOI: 10.1007/s00380-021-01841-y
Source DB: PubMed Journal: Heart Vessels ISSN: 0910-8327 Impact factor: 2.037