| Literature DB >> 33831253 |
Zachary J Brown1, Jordan M Cloyd1.
Abstract
For patients with localized pancreatic cancer, neoadjuvant therapy (NT) is increasingly delivered before surgery to maximize the receipt of multimodality therapy and the odds of a margin-negative resection. Three decades of refining the use of NT have led to its acceptance as a valid treatment approach for pancreatic adenocarcinoma. In this review, we discuss the rationale for and recent global trends in the utilization of NT for patients with pancreatic cancer.Entities:
Keywords: FOLFIRINOX; neoadjuvant chemotherapy; pancreatic cancer; pancreatoduodenectomy; preoperative therapy; whipple
Mesh:
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Year: 2021 PMID: 33831253 DOI: 10.1002/jso.26384
Source DB: PubMed Journal: J Surg Oncol ISSN: 0022-4790 Impact factor: 3.454