Literature DB >> 33828431

Optic Neuritis After a Snakebite: A Diagnostic Dilemma.

Jeyhan Dhabhar1, Varshil Mehta2, Nimit Desai3.   

Abstract

Background: Snakebite is one of the major causes of morbidity and mortality in India, particularly in rural regions. Of the 57 known venomous species of snakes in India, the 4 most dangerous snakes are the cobra, the common krait, the Russell viper, and the saw-scaled viper. Of these, the snakes commonly implicated with neurotoxicity are the cobra and the common krait-both elapidae. Acute neuromuscular weakness with respiratory system involvement is the most lethal neurotoxic effect. Case Report: A 24-year-old female was brought to the emergency department in an unresponsive state with a history of snakebite on the left foot. The patient was intubated, mechanically ventilated, and promptly started on snake antivenom and anticholinesterase agents. The patient improved significantly and was extubated. On day 6, she developed blurred vision and slurred speech. She was diagnosed with bilateral optic neuropathy and treated with repeat snake antivenom and steroids. She improved significantly and was discharged on day 14.
Conclusion: When a person is bitten by a venomous snake, antivenom is the mainstay of treatment, but clinicians must also consider possible reactions and complications. Optic neuritis following a snakebite is rare but does occur. The prognosis is generally good if clinical suspicion for such a complication is strong, the snake is identified, and the patient receives timely treatment with steroids. ©2021 by the author(s); Creative Commons Attribution License (CC BY).

Entities:  

Keywords:  Delayed diagnosis; elapidae; neurotoxicity syndromes; snake bites

Year:  2021        PMID: 33828431      PMCID: PMC7993431          DOI: 10.31486/toj.19.0014

Source DB:  PubMed          Journal:  Ochsner J        ISSN: 1524-5012


  13 in total

1.  Allergy to antivenine serum.

Authors:  S P MATHUR
Journal:  Br J Ophthalmol       Date:  1959-01       Impact factor: 4.638

2.  Blindness after snake-bite.

Authors:  A GUTTMANN-FRIEDMANN
Journal:  Br J Ophthalmol       Date:  1956-01       Impact factor: 4.638

3.  Loss of sight following snake bite.

Authors:  R C DAVENPORT; F H BUDDEN
Journal:  Br J Ophthalmol       Date:  1953-02       Impact factor: 4.638

Review 4.  Snakebite envenoming.

Authors:  José María Gutiérrez; Juan J Calvete; Abdulrazaq G Habib; Robert A Harrison; David J Williams; David A Warrell
Journal:  Nat Rev Dis Primers       Date:  2017-09-14       Impact factor: 52.329

5.  Bilateral blindness following snake bite.

Authors:  A S Sahai; R H Sinha
Journal:  Indian J Ophthalmol       Date:  1978-10       Impact factor: 1.848

6.  Optic neuritis and ophthalmoplegia caused by snake bite.

Authors:  K V Rao
Journal:  Indian J Ophthalmol       Date:  1981-10       Impact factor: 1.848

7.  Neurological manifestations of snake bite in Sri Lanka.

Authors:  U Seneviratne; S Dissanayake
Journal:  J Postgrad Med       Date:  2002 Oct-Dec       Impact factor: 1.476

8.  Snakebite mortality in India: a nationally representative mortality survey.

Authors:  Bijayeeni Mohapatra; David A Warrell; Wilson Suraweera; Prakash Bhatia; Neeraj Dhingra; Raju M Jotkar; Peter S Rodriguez; Kaushik Mishra; Romulus Whitaker; Prabhat Jha
Journal:  PLoS Negl Trop Dis       Date:  2011-04-12

9.  The global burden of snakebite: a literature analysis and modelling based on regional estimates of envenoming and deaths.

Authors:  Anuradhani Kasturiratne; A Rajitha Wickremasinghe; Nilanthi de Silva; N Kithsiri Gunawardena; Arunasalam Pathmeswaran; Ranjan Premaratna; Lorenzo Savioli; David G Lalloo; H Janaka de Silva
Journal:  PLoS Med       Date:  2008-11-04       Impact factor: 11.069

Review 10.  Neurotoxicity in snakebite--the limits of our knowledge.

Authors:  Udaya K Ranawaka; David G Lalloo; H Janaka de Silva
Journal:  PLoS Negl Trop Dis       Date:  2013-10-10
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  1 in total

1.  Delayed Visual Loss in a Patient with Snake Bite: Case Report of an Unusual Neuro-Ophthalmic Presentation.

Authors:  Sandip Kuikel; Suman Rimal; Rajeev Ojha; Sanjeeta Sitaula; Ragesh Karn; Bikram Gajurel; Reema Rajbhandari; Niraj Gautam; Sunanda Paudel; Aashish Shrestha
Journal:  Case Rep Neurol       Date:  2022-03-24
  1 in total

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