Literature DB >> 33822902

Joint anatomy in axial spondyloarthritis: strong associations between sacroiliac joint form variation and symptomatic disease.

Katharina Ziegeler1, Virginie Kreutzinger2, Fabian Proft3, Denis Poddubnyy3, Kay Geert A Hermann1, Torsten Diekhoff1.   

Abstract

OBJECTIVES: The aim of this investigation was to determine the prevalence of variant SI joint forms in symptomatic patients with mechanical joint disease (MJD) and axial SpA (axSpA) compared with control patients.
METHOD: A total of 973 patients were included in this cross-sectional study (95 axSpA; 61 MJD; 817 controls); clinical diagnosis, age and gender were noted. An established scoring system was used to classify joint forms on CT scans of the pelvis. Frequencies of joint forms were compared between groups (axSpA; MJD; controls).
RESULTS: Patients with MJD exhibited the highest proportion of atypical joints (80.3% in MJD vs 44.1% in axSpA and 37.5% in controls; P < 0.001). Overall, females had a significantly higher proportion of atypical joints than men (65.0 vs 17.8%; P < 0.001); proportions of atypical joints were significantly higher in males with symptomatic joint disease than in male controls: 32.2% in axSpA, 55.0% in MJD and 13.9% in controls; P ≤ 0.001. Two specific joint forms were significantly more prevalent in symptomatic patients than in controls: the iliosacral complex (16.2 vs 4.2%; P < 0.001) and the crescent-shaped ilium (9.1 vs 2.8%; P < 0.05).
CONCLUSIONS: Our data demonstrate a strong association between atypical joint forms and symptomatic joint disease.
© The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Entities:  

Keywords:  ankylosing spondylitis; computed tomography; diagnostic imaging; sacroiliitis

Mesh:

Year:  2021        PMID: 33822902     DOI: 10.1093/rheumatology/keab318

Source DB:  PubMed          Journal:  Rheumatology (Oxford)        ISSN: 1462-0324            Impact factor:   7.580


  5 in total

1.  Distribution of Acute and Chronic Lesions in the Sacroiliac Joints of Patients with Axial Spondyloarthritis.

Authors:  Churong Lin; Dong Liu; Budian Liu; Jieruo Gu
Journal:  Int J Gen Med       Date:  2022-01-04

2.  Unexpected Sex Differences in the Relationship of Sacroiliac Joint and Lumbar Spine Degeneration.

Authors:  Maximilian Muellner; Virginie Kreutzinger; Luis Becker; Torsten Diekhoff; Matthias Pumberger; Friederike Schömig; Mark Heyland; Katharina Ziegeler
Journal:  Diagnostics (Basel)       Date:  2022-01-21

Review 3.  A glance into the future of diagnosis and treatment of spondyloarthritis.

Authors:  Victoria Navarro-Compán; Joerg Ermann; Denis Poddubnyy
Journal:  Ther Adv Musculoskelet Dis       Date:  2022-07-22       Impact factor: 3.625

4.  Anatomical variation at the sacroiliac joints in young adults: estimated prevalence by CT and concomitant diagnostics by MRI.

Authors:  Rosa Marie Kiil; Anne Grethe Jurik; Anna Zejden
Journal:  Skeletal Radiol       Date:  2021-07-15       Impact factor: 2.199

5.  Differences in topographical location of sacroiliac joint MRI lesions in patients with early axial spondyloarthritis and mechanical back pain.

Authors:  Rosa Marie Kiil; Clara E Mistegaard; Anne Gitte Loft; Anna Zejden; Oliver Hendricks; Anne Grethe Jurik
Journal:  Arthritis Res Ther       Date:  2022-03-24       Impact factor: 5.156

  5 in total

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