Literature DB >> 3382271

Pancytopenia related to azathioprine in rheumatoid arthritis.

M E Jeurissen1, A M Boerbooms, L B van de Putte.   

Abstract

Two patients with rheumatoid arthritis developed pancytopenia during treatment with azathioprine 100 mg daily. In one patient this side effect occurred after three weeks, in the other after eight weeks of treatment. Rapid fall of platelets in one patient necessitated platelet transfusion. In the other patient additional treatment with allopurinol was probably responsible for the toxic effect. Haematological side effects of azathioprine are discussed.

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Year:  1988        PMID： 3382271      PMCID： PMC1003554          DOI： 10.1136/ard.47.6.503

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  4 in total

1.  [Pancytopenia following combination treatment with allopurinol and azathioprine].

Authors:  P Glogner; N Heni
Journal:  Med Welt       Date:  1976-08-13

2.  [Myelosuppression with macrocytic anaemia and leucopenia during treatment with azathioprine in myasthenia gravis].

Authors:  H Reinicke; F W Weber; T U Hausamen
Journal:  Dtsch Med Wochenschr       Date:  1982-10-22       Impact factor: 0.628

3.  Azathioprine-induced pure red blood cell aplasia.

Authors:  C W Old; E P Flannery; T M Grogan; W H Stone; R P San Antonio
Journal:  JAMA       Date:  1978-08-11       Impact factor: 56.272

4.  Rheumatoid arthritis: treatment with azathioprine (IMURAN (R)). Clinical side-effects and laboratory abnormalities.

Authors:  J K Whisnant; J Pelkey
Journal:  Ann Rheum Dis       Date:  1982       Impact factor: 19.103
  4 in total
  10 in total

1.  Modeling the Outcome of Systematic TPMT Genotyping or Phenotyping Before Azathioprine Prescription: A Cost-Effectiveness Analysis.

Authors:  Kevin Zarca; Isabelle Durand-Zaleski; Marie-Anne Loriot; Gilles Chatellier; Nicolas Pallet
Journal:  Mol Diagn Ther       Date:  2019-06       Impact factor: 4.074

2.  Purine enzyme activities in recent onset rheumatoid arthritis: are there differences between patients and healthy controls?

Authors:  J N Stolk; A M Boerbooms; R A De Abreu; P J Kerstens; D G de Koning; R de Graaf; J Mulder; L B van de Putte
Journal:  Ann Rheum Dis       Date:  1996-10       Impact factor: 19.103

Review 3.  Anaemia in rheumatoid arthritis: pathogenesis, diagnosis and treatment.

Authors:  G Vreugdenhil; A J Swaak
Journal:  Rheumatol Int       Date:  1990       Impact factor: 2.631

Review 4.  The role of erythropoietin in the anaemia of chronic disease in rheumatoid arthritis.

Authors:  G Vreugdenhil; A J Swaak
Journal:  Clin Rheumatol       Date:  1990-03       Impact factor: 2.980

5.  Association of thiopurine methyltransferase status with azathioprine side effects in Chinese patients with systemic lupus erythematosus.

Authors:  Dongying Chen; Fan Lian; Shiwen Yuan; Yixi Wang; Zhongping Zhan; Yujin Ye; Qian Qiu; Hanshi Xu; Liuqin Liang; Xiuyan Yang
Journal:  Clin Rheumatol       Date:  2013-12-10       Impact factor: 2.980

6.  Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years of experience.

Authors:  W R Connell; M A Kamm; J K Ritchie; J E Lennard-Jones
Journal:  Gut       Date:  1993-08       Impact factor: 23.059

7.  The haemotoxicity of azathioprine in repeat dose studies in the female CD-1 mouse.

Authors:  Gemma Molyneux; Frances M Gibson; Christabelle M Chen; Harpal K Marway; Sean McKeag; Charles V J Mifsud; Andrew M Pilling; Matthew J Whayman; John A Turton
Journal:  Int J Exp Pathol       Date:  2008-04       Impact factor: 1.925

8.  Monitoring of nonsteroidal immunosuppressive drugs in patients with lung disease and lung transplant recipients: American College of Chest Physicians evidence-based clinical practice guidelines.

Authors:  Robert P Baughman; Keith C Meyer; Ian Nathanson; Luis Angel; Sangeeta M Bhorade; Kevin M Chan; Daniel Culver; Christopher G Harrod; Mary S Hayney; Kristen B Highland; Andrew H Limper; Herbert Patrick; Charlie Strange; Timothy Whelan
Journal:  Chest       Date:  2012-11       Impact factor: 9.410

Review 9.  Pancytopenia related to azathioprine--an enzyme deficiency caused by a common genetic polymorphism: a review.

Authors:  A Anstey; L Lennard; S C Mayou; J D Kirby
Journal:  J R Soc Med       Date:  1992-12       Impact factor: 18.000

10.  High discontinuation rate of azathioprine in autoimmune hepatitis, independent of time of treatment initiation.

Authors:  Simon Pape; Tom J G Gevers; Jan Maarten Vrolijk; Bart van Hoek; Gerd Bouma; Carin M J van Nieuwkerk; Richard Taubert; Elmar Jaeckel; Michael P Manns; Maria Papp; Nora Sipeki; Felix Stickel; Cumali Efe; Ersan Ozaslan; Tugrul Purnak; Frederik Nevens; Dominik J N Kessener; Alisan Kahraman; Heiner Wedemeyer; Johannes Hartl; Christoph Schramm; Ansgar W Lohse; Michael A Heneghan; Joost P H Drenth
Journal:  Liver Int       Date:  2020-06-11       Impact factor: 5.828
  10 in total

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