| Literature DB >> 33821663 |
Le Yang1, Zhihong Qiu1, Jintao Wu1, Jianyou Zhao1, Tong Shen1, Xuan Huang2, Zhong-Quan Liu1.
Abstract
A direct and site-specific alkylation of (sp3)C-H bond with aliphatic boronic acid was achieved. By simply heating glycinates and amines together with alkylboronic acids under an oxygen atmosphere, a variety of unnatural α-amino acids and peptides could be obtained in good yields.Entities:
Year: 2021 PMID： 33821663 DOI： 10.1021/acs.orglett.1c00948
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005