Literature DB >> 33817438

Bilateral retinal toxicity as a result of poisoning with pure iodine.

Bahadir Camgoz Esra1, Sakir Goker Yasin1.   

Abstract

Iodine is an essential mineral that is necessary for the synthesis of thyroid hormones, which can cause many diseases in the body. The application of adding potassium iodate to table salts started in Turkey in 1998. High doses of iodate cause retinal toxicity, leading to significant vision loss. A 42-year-old paranoid schizophrenic patient who attempted suicide with pure iodine was admitted with bilateral vision loss. Widespread retinal pigment epithelium (RPE), ellipsoid zone (EZ) and interdigitation zone (IZ) damage were present in the optical coherence tomography (OCT) assessment. Fundus autofluorescence (FAF) findings, which included hypoautofluorescence areas that supported this condition, were also found. In conclusion, iodate in high doses is toxic on RPE, EZ and IZ. This situation could be irreversible depending on the dose. ©Romanian Society of Ophthalmology.

Entities:  

Keywords:  fundus autofluorescence; iodine toxicity; optical coherence tomography; toxic retinopathy

Year:  2021        PMID: 33817438      PMCID: PMC7995510          DOI: 10.22336/rjo.2021.14

Source DB:  PubMed          Journal:  Rom J Ophthalmol        ISSN: 2457-4325


  10 in total

1.  Retinal degeneration rat model: A study on the structural and functional changes in the retina following injection of sodium iodate.

Authors:  Avin Ee-Hwan Koh; Hiba Amer Alsaeedi; Munirah Binti Abd Rashid; Chenshen Lam; Mohd Hairul Nizam Harun; Muhamad Fakhri Bin Mohd Saleh; Chi D Luu; S Suresh Kumar; Min Hwei Ng; Hazlita Mohd Isa; Sue Ngein Leow; Kong Yong Then; Mae-Lynn Catherine Bastion; Mohammed Safwan Ali Khan; Pooi Ling Mok
Journal:  J Photochem Photobiol B       Date:  2019-05-22       Impact factor: 6.252

2.  Irreversible Photoreceptors and RPE Cells Damage by Intravenous Sodium Iodate in Mice Is Related to Macrophage Accumulation.

Authors:  Mayu Moriguchi; Shinsuke Nakamura; Yuki Inoue; Anri Nishinaka; Maho Nakamura; Masamitsu Shimazawa; Hideaki Hara
Journal:  Invest Ophthalmol Vis Sci       Date:  2018-07-02       Impact factor: 4.799

Review 3.  Iodine deficiency in the world: where do we stand at the turn of the century?

Authors:  F Delange; B de Benoist; E Pretell; J T Dunn
Journal:  Thyroid       Date:  2001-05       Impact factor: 6.568

4.  Potassium iodate toxic retinopathy: a report of five cases.

Authors:  A Singalavanija; N Ruangvaravate; D Dulayajinda
Journal:  Retina       Date:  2000       Impact factor: 4.256

Review 5.  Iodine deficiency: Clinical implications.

Authors:  Soamsiri Niwattisaiwong; Kenneth D Burman; Melissa Li-Ng
Journal:  Cleve Clin J Med       Date:  2017-03       Impact factor: 2.321

6.  Iodine status and goiter prevalence in Turkey before mandatory iodization.

Authors:  G Erdoğan; M F Erdogan; R Emral; M Baştemir; H Sav; D Haznedaroğlu; M Ustündağ; R Köse; N Kamel; Y Genç
Journal:  J Endocrinol Invest       Date:  2002-03       Impact factor: 4.256

7.  Iodine deficiency disorders (IDD) and their eradication.

Authors:  B S Hetzel
Journal:  Lancet       Date:  1983-11-12       Impact factor: 79.321

8.  Fundus autofluorescence (FAF) non-invasively identifies chorioretinal toxicity in a rat model of retinal pigment epithelium (RPE) damage.

Authors:  David Sung Hyeon Baek; Huiyuan Liang; Xu Zhao; Natalie Pankova; Hai Wang; Shelley Boyd
Journal:  J Pharmacol Toxicol Methods       Date:  2014-09-06       Impact factor: 1.950

9.  Iodate induced toxic retinopathy: a case report.

Authors:  Y C Venu Gopal Reddy; Anuj Sharma; Adheesh P Shetty; Syed Mohideen Abdul Kader
Journal:  Int J Retina Vitreous       Date:  2018-08-01

10.  The Results of 16 Years of Iodization: Assessment of Iodine Deficiency Among School-age Children in Antalya, Turkey

Authors:  Gamze Çelmeli; Yusuf Çürek; İkbal Özen Küçükçetin; Zümrüt Arslan Gülten; Sebahat Özdem; Sema Akçurin; İffet Bircan
Journal:  J Clin Res Pediatr Endocrinol       Date:  2020-01-17
  10 in total

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