Literature DB >> 33816903

RIdeogram: drawing SVG graphics to visualize and map genome-wide data on the idiograms.

Zhaodong Hao1,2, Dekang Lv3, Ying Ge3, Jisen Shi1, Dolf Weijers2, Guangchuang Yu4, Jinhui Chen1.   

Abstract

BACKGROUND: Owing to the rapid advances in DNA sequencing technologies, whole genome from more and more species are becoming available at increasing pace. For whole-genome analysis, idiograms provide a very popular, intuitive and effective way to map and visualize the genome-wide information, such as GC content, gene and repeat density, DNA methylation distribution, genomic synteny, etc. However, most available software programs and web servers are available only for a few model species, such as human, mouse and fly, or have limited application scenarios. As more and more non-model species are sequenced with chromosome-level assembly being available, tools that can generate idiograms for a broad range of species and be capable of visualizing more data types are needed to help better understanding fundamental genome characteristics.
RESULTS: The R package RIdeogram allows users to build high-quality idiograms of any species of interest. It can map continuous and discrete genome-wide data on the idiograms and visualize them in a heat map and track labels, respectively.
CONCLUSION: The visualization of genome-wide data mapping and comparison allow users to quickly establish a clear impression of the chromosomal distribution pattern, thus making RIdeogram a useful tool for any researchers working with omics. ©2020 Hao et al.

Entities:  

Keywords:  Chromosome; Data visualization; Genome; Idiogram; R package

Year:  2020        PMID: 33816903      PMCID: PMC7924719          DOI: 10.7717/peerj-cs.251

Source DB:  PubMed          Journal:  PeerJ Comput Sci        ISSN: 2376-5992


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