| Literature DB >> 33815616 |
Ovidiu Stiru1,2, Anca Dragan1, Cristina Adamache1, Petru Razvan Dragulescu1, Carmen Stiru3, Adrian Tulin4,5, Nicolae Bacalbasa6,7,8, Irina Balescu9, Camelia Diaconu10,11, Roxana Carmen Geana1, Cornel Savu12,13, Vlad Anton Iliescu1,2.
Abstract
Paragangliomas are extremely rare neuroendocrine tumors. We report a case of a 44-year-old man with hypertension who presented a tumoral mass located retroperitoneally at the aortic bifurcation which included both the common iliac arteries and the posterior left iliac vein, who experienced an unpredictable intraoperative cardiac arrest with electromechanical dissociation at 5 min after laparotomy. After successful resuscitation and hemodynamic stability, the lesion was fully excised. In the course of tumor manipulation, the patient developed a major hypertensive crisis with peak systolic blood pressure over 280 mmHg. Pathologic examination revealed the presence of diffuse proliferation of large and medium-sized mature adipocytes consistent with paraganglioma diagnosis. The patient was discharged at home on the seventh postoperative day. He did not present evidence of recurrence at the one-year follow-up. In conclusion, paragangliomas can require particular management due to their location but also due to their capacity to discharge substances which might induce life-threatening intraoperative complications.Entities:
Keywords: arterial hypertension; catecholamines; neuroendocrine tumors; paraganglioma; vanyl mandelic acid
Year: 2021 PMID: 33815616 PMCID: PMC8014983 DOI: 10.3892/etm.2021.9975
Source DB: PubMed Journal: Exp Ther Med ISSN: 1792-0981 Impact factor: 2.447