Literature DB >> 33814843

Malignancy in an Undescended Intra-abdominal Testis: a Single Institution Experience.

Vikas Gupta1, Ashwin Giridhar1, Rakesh Sharma1, Syed Murtaza Ahmed1, K V V N Raju1, T Subramanyeshwar Rao1.   

Abstract

Cryptorchidism is one of the most common congenital anomalies of the genitourinary tract, encountered in 1% of men. The cancer risk in an ectopic testis is 40 times higher than a scrotal testis. However, not much literature is available on the management of this rare presentation of testicular cancer. A retrospective analysis was conducted at our institute of patients who were diagnosed with carcinoma in an undescended intra-abdominal testis between 2014 and 2019. Patients with an intra-abdominal mass with an empty hemiscrotum/scrotum were included in the study. In all 10 patients were identified with a mean age of 32 years. Four patients were non-seminomatous germ cell tumors, and other 6 were seminomatous tumors. Five were in stage I, two in stage II, and three in stage III. Six patients received induction chemotherapy with bleomycin, etoposide, and cisplatin, and four had complete response. Five patients underwent laparoscopic excision, and five underwent open surgery. Two patients with bilateral (B/L) cryptorchidism underwent contralateral orchidopexy. Two patients with B/L intra-abdominal gonads and uterus underwent excision of the malignant testicular mass with removal of atrophic uterus and contralateral dysgenetic gonad. One patient developed peritoneal recurrence within 3 months of completion of surgery. Both recurrence-free and overall survival were 90% after a median follow-up of 35 months. Malignancy in an undescended intra-abdominal testis is a rare presentation of testicular cancer, diagnosis of which requires a sharp correlation between clinical and radiological findings. There management and prognosis remains similar to classical testicular cancer. © Indian Association of Surgical Oncology 2021.

Entities:  

Keywords:  Intra-abdominal testis; Testicular cancer; Undescended testis

Year:  2021        PMID: 33814843      PMCID: PMC7960876          DOI: 10.1007/s13193-020-01262-9

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  25 in total

1.  Correction of cryptorchidism and testicular cancer.

Authors:  Charlotte Myrup; Tine H Schnack; Jan Wohlfahrt
Journal:  N Engl J Med       Date:  2007-08-23       Impact factor: 91.245

2.  Seminomas complicating undescended intraabdominal testes in patients with prior negative findings from surgical exploration.

Authors:  F H Miller; W S Whitney; S W Fitzgerald; E I Miller
Journal:  AJR Am J Roentgenol       Date:  1999-02       Impact factor: 3.959

3.  Cryptorchidism and testicular neoplasia.

Authors:  Kamal E Bani-Hani; Yousef S Matani; Ibrahim H Bani-Hani
Journal:  Saudi Med J       Date:  2003-02       Impact factor: 1.484

4.  Risk of testicular cancer in cohort of boys with cryptorchidism.

Authors:  A J Swerdlow; C D Higgins; M C Pike
Journal:  BMJ       Date:  1997-05-24

5.  Improved management of abdominal undescended testicular tumors with bulky confluent retroperitoneal nodal metastases.

Authors:  J N Kulkarni; S M Desai; G K Phadke; H B Tongaonkar
Journal:  J Urol       Date:  1996-10       Impact factor: 7.450

6.  Contemporary trends in postchemotherapy retroperitoneal lymph node dissection: Additional procedures and perioperative complications.

Authors:  Clint Cary; Timothy A Masterson; Richard Bihrle; Richard S Foster
Journal:  Urol Oncol       Date:  2015-01-05       Impact factor: 3.498

Review 7.  Cryptorchidism and testicular cancer: separating fact from fiction.

Authors:  Hadley M Wood; Jack S Elder
Journal:  J Urol       Date:  2008-12-13       Impact factor: 7.450

8.  Unresolved abdominal mass.

Authors:  B Shrestha; J L Baidya
Journal:  Kathmandu Univ Med J (KUMJ)       Date:  2009 Jan- Mar

9.  Cryptorchidism and testicular cancer.

Authors:  M A Batata; W F Whitmore; F C Chu; B S Hilaris; J Loh; H Grabstald; R Golbey
Journal:  J Urol       Date:  1980-09       Impact factor: 7.450

10.  Germ cell development in the postnatal testis: the key to prevent malignancy in cryptorchidism?

Authors:  John M Hutson; Ruili Li; Bridget R Southwell; Bodil L Petersen; Jorgen Thorup; Dina Cortes
Journal:  Front Endocrinol (Lausanne)       Date:  2013-01-03       Impact factor: 5.555

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  1 in total

1.  Unusual presentation of an intra-abdominal testicular seminoma in an adult.

Authors:  Houssem Ben Hadj Alouane; Kheireddine Mrad Dali; Mohamed Anouar Madani; Kays Chaker; Yassine Nouira
Journal:  Urol Case Rep       Date:  2022-05-20
  1 in total

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