Literature DB >> 33814500

BCR/ABL1-positive B-lymphoblastic Lymphoma Successfully Treated with Dasatinib-combined Chemotherapy.

Chika Yamada1, Yoshimitsu Shimomura1, Kimimori Kamijyo1, Madoka Kanda-Kato1, Satoshi Yoshioka1, Daisuke Yamashita2, Takayuki Ishikawa1.   

Abstract

We herein report a rare case of BCR-ABL1-positive B-lymphoblastic lymphoma (B-LBL). An 18-year-old woman had a history of persistent left-sided chest pain. Positron emission tomography showed increased metabolic activity in the fifth rib, duodenum, and pancreas. The pathological findings of the pancreas, duodenum, and bone marrow confirmed the diagnosis of B-LBL. Polymerase chain reaction of duodenum and bone marrow also revealed a minor BCR-ABL1 fusion gene. She was diagnosed with BCR-ABL1-positive B-LBL and administered dasatinib and prednisolone. She achieved complete remission two weeks after the initiation of the treatment. She received stem cell transplantation after consolidation chemotherapy and sustained complete remission.

Entities:  

Keywords:  :BCR-ABL1; B-lymphoblastic lymphoma; and dasatinib; tyrosine kinase inhibitors

Year:  2021        PMID: 33814500     DOI: 10.2169/internalmedicine.7066-21

Source DB:  PubMed          Journal:  Intern Med        ISSN: 0918-2918            Impact factor:   1.271


  2 in total

1.  Primary Testicular and Cutaneous Philadelphia Chromosome Positive B-Cell Lymphoblastic Lymphoma: A Rare Case and Review.

Authors:  Qiuxia Yu; Gaoxiang Wang; Jue Wang; Wei Zhang; Li Meng; Yang Cao
Journal:  Cancer Manag Res       Date:  2022-04-21       Impact factor: 3.602

2.  Philadelphia chromosome-positive B-lymphoblastic lymphoma successfully treated with chemotherapy regimen containing imatinib: A rare case report and literature review.

Authors:  Xiaoning Li; Weijie Cao; Suping Zhang; Li Li; Yingmei Li; Zhongxing Jiang; Dingming Wan; Jifeng Yu
Journal:  Medicine (Baltimore)       Date:  2021-06-11       Impact factor: 1.817

  2 in total

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