Literature DB >> 33813580

Under the Skin: The Relationship Between Subcutaneous Injection and Skin Infections Among People Who Inject Drugs.

Christina E Freibott1, Kristina T Phillips, Bradley J Anderson, Catherine Stewart, Jane M Liebschutz, Michael D Stein.   

Abstract

OBJECTIVES: People who inject drugs (PWID) are at increased risk for numerous negative health outcomes. Subcutaneous injections (aka skin popping) can result in greater risk of skin and soft tissue infections (SSTIs), but less is known about PWID who choose this route of administration. This study compares subcutaneous injectors to intravenous injectors, characterizes those who inject subcutaneously, and examines whether subcutaneous injection is associated with SSTIs in the past year.
METHODS: A cohort of hospitalized PWID (n = 252) were interviewed regarding injection-related behaviors, history of SSTI, and knowledge of subcutaneous injection risk. We examined differences between those who do and do not inject subcutaneously and used a negative binomial regression model to estimate adjusted odds associating subcutaneous injection and SSTI.
RESULTS: Participants averaged 38 years, with 58.3% male, 59.5% White, 20.6% Black, and 15.9% Latinx. PWID who performed subcutaneous injection were not demographically different from other PWID; however, the mean rate of past year SSTIs was higher for persons injecting subcutaneously than for those who did not (1.98 vs 0.96, P < 0.001). Persons injecting subcutaneously did not differ from those who injected intravenously in terms of their knowledge of subcutaneous injection risk (P = 0.112) and knowledge score was not associated with SSTIs (P = 0.457).
CONCLUSIONS: PWID who perform subcutaneous injections are demographically similar to other PWID but had higher rates of past year SSTIs. Knowledge of subcutaneous injection risk was not associated with SSTI risk.
Copyright © 2021 American Society of Addiction Medicine.

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Year:  2022        PMID: 33813580      PMCID: PMC8486890          DOI: 10.1097/ADM.0000000000000844

Source DB:  PubMed          Journal:  J Addict Med        ISSN: 1932-0620            Impact factor:   3.702


  31 in total

1.  High prevalence of abscesses and cellulitis among community-recruited injection drug users in San Francisco.

Authors:  I A Binswanger; A H Kral; R N Bluthenthal; D J Rybold; B R Edlin
Journal:  Clin Infect Dis       Date:  2000-03       Impact factor: 9.079

Review 2.  Skin and soft tissue infections in injection drug users.

Authors:  John R Ebright; Barbara Pieper
Journal:  Infect Dis Clin North Am       Date:  2002-09       Impact factor: 5.982

3.  Reducing the adverse impact of injection drug use in Canada.

Authors:  Kevin B Laupland; John M Embil
Journal:  Can J Infect Dis Med Microbiol       Date:  2012       Impact factor: 2.471

4.  Fire in the vein: Heroin acidity and its proximal effect on users' health.

Authors:  Daniel Ciccarone; Magdalena Harris
Journal:  Int J Drug Policy       Date:  2015-04-17

5.  Social structural factors that shape assisted injecting practices among injection drug users in Vancouver, Canada: a qualitative study.

Authors:  Nadia Fairbairn; Will Small; Natasha Van Borek; Evan Wood; Thomas Kerr
Journal:  Harm Reduct J       Date:  2010-08-31

6.  Risk factors for shooting gallery use and cessation among intravenous drug users.

Authors:  D D Celentano; D Vlahov; S Cohn; J C Anthony; L Solomon; K E Nelson
Journal:  Am J Public Health       Date:  1991-10       Impact factor: 9.308

7.  Women's injection drug practices in their own words: a qualitative study.

Authors:  Ellen Tuchman
Journal:  Harm Reduct J       Date:  2015-03-07

8.  Infections with spore-forming bacteria in persons who inject drugs, 2000-2009.

Authors:  Norah E Palmateer; Vivian D Hope; Kirsty Roy; Andrea Marongiu; Joanne M White; Kathie A Grant; Colin N Ramsay; David J Goldberg; Fortune Ncube
Journal:  Emerg Infect Dis       Date:  2013-01       Impact factor: 6.883

9.  Risk factors for developing a cutaneous injection-related infection among injection drug users: a cohort study.

Authors:  Elisa Lloyd-Smith; Evan Wood; Ruth Zhang; Mark W Tyndall; Julio S G Montaner; Thomas Kerr
Journal:  BMC Public Health       Date:  2008-12-09       Impact factor: 3.295

10.  Self-care habits among people who inject drugs with skin and soft tissue infections: a qualitative analysis.

Authors:  Andrew R Gilbert; Julia L Hellman; Michael S Wilkes; Vaughan W Rees; Phillip J Summers
Journal:  Harm Reduct J       Date:  2019-12-12
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