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Literature DB >> 33811114

T Cells as the Future of Cancer Therapy.

Abstract

In the next 10 years, gene-engineered T-cell therapies have the potential to provide broad benefit for the treatment of patients with cancer. Advances in immunology, molecular biology, and bioengineering allow the design of gene-engineered T cells that actively target metastatic lesions, specifically recognize and kill cancer cells, and maintain long-term immunologic memory. ©2021 American Association for Cancer Research.

Entities: Chemical

Mesh：

Year: 2021 PMID： 33811114 PMCID： PMC8082738 DOI： 10.1158/2159-8290.CD-21-0022

Source DB: PubMed Journal: Cancer Discov ISSN： 2159-8274 Impact factor: 38.272

15 in total

Review 1. Adoptive immunotherapy for cancer: harnessing the T cell response.

Authors: Nicholas P Restifo; Mark E Dudley; Steven A Rosenberg
Journal: Nat Rev Immunol Date: 2012-03-22 Impact factor: 53.106

Review 2. Chimeric Antigen Receptor Therapy.

Authors: Carl H June; Michel Sadelain
Journal: N Engl J Med Date: 2018-07-05 Impact factor: 91.245

3. Precise T cell recognition programs designed by transcriptionally linking multiple receptors.

Authors: Jasper Z Williams; Greg M Allen; Devan Shah; Igal S Sterin; Ki H Kim; Vivian P Garcia; Gavin E Shavey; Wei Yu; Cristina Puig-Saus; Jennifer Tsoi; Antoni Ribas; Kole T Roybal; Wendell A Lim
Journal: Science Date: 2020-11-27 Impact factor: 47.728

4. Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes.

Authors: Jonathan T Sockolosky; Eleonora Trotta; Giulia Parisi; Lora Picton; Leon L Su; Alan C Le; Akanksha Chhabra; Stephanie L Silveria; Benson M George; Indigo C King; Matthew R Tiffany; Kevin Jude; Leah V Sibener; David Baker; Judith A Shizuru; Antoni Ribas; Jeffrey A Bluestone; K Christopher Garcia
Journal: Science Date: 2018-03-02 Impact factor: 47.728

5. Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells.

Authors: Waseem Qasim; Hong Zhan; Sujith Samarasinghe; Stuart Adams; Persis Amrolia; Sian Stafford; Katie Butler; Christine Rivat; Gary Wright; Kathy Somana; Sara Ghorashian; Danielle Pinner; Gul Ahsan; Kimberly Gilmour; Giovanna Lucchini; Sarah Inglott; William Mifsud; Robert Chiesa; Karl S Peggs; Lucas Chan; Farzin Farzeneh; Adrian J Thrasher; Ajay Vora; Martin Pule; Paul Veys
Journal: Sci Transl Med Date: 2017-01-25 Impact factor: 17.956

6. Synthekines are surrogate cytokine and growth factor agonists that compel signaling through non-natural receptor dimers.

Authors: Ignacio Moraga; Jamie B Spangler; Juan L Mendoza; Milica Gakovic; Tom S Wehrman; Peter Krutzik; K Christopher Garcia
Journal: Elife Date: 2017-05-12 Impact factor: 8.140

7. Generation of mature T cells from human hematopoietic stem and progenitor cells in artificial thymic organoids.

Authors: Christopher S Seet; Chongbin He; Michael T Bethune; Suwen Li; Brent Chick; Eric H Gschweng; Yuhua Zhu; Kenneth Kim; Donald B Kohn; David Baltimore; Gay M Crooks; Amélie Montel-Hagen
Journal: Nat Methods Date: 2017-04-03 Impact factor: 28.547

8. Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood.

Authors: Songming Peng; Jesse M Zaretsky; Alphonsus H C Ng; William Chour; Michael T Bethune; Jongchan Choi; Alice Hsu; Elizabeth Holman; Xiaozhe Ding; Katherine Guo; Jungwoo Kim; Alexander M Xu; John E Heath; Won Jun Noh; Jing Zhou; Yapeng Su; Yue Lu; Jami McLaughlin; Donghui Cheng; Owen N Witte; David Baltimore; Antoni Ribas; James R Heath
Journal: Cell Rep Date: 2019-09-03 Impact factor: 9.423

9. Reprogramming human T cell function and specificity with non-viral genome targeting.

Authors: Theodore L Roth; Cristina Puig-Saus; Ruby Yu; Eric Shifrut; Julia Carnevale; P Jonathan Li; Joseph Hiatt; Justin Saco; Paige Krystofinski; Han Li; Victoria Tobin; David N Nguyen; Michael R Lee; Amy L Putnam; Andrea L Ferris; Jeff W Chen; Jean-Nicolas Schickel; Laurence Pellerin; David Carmody; Gorka Alkorta-Aranburu; Daniela Del Gaudio; Hiroyuki Matsumoto; Montse Morell; Ying Mao; Min Cho; Rolen M Quadros; Channabasavaiah B Gurumurthy; Baz Smith; Michael Haugwitz; Stephen H Hughes; Jonathan S Weissman; Kathrin Schumann; Jonathan H Esensten; Andrew P May; Alan Ashworth; Gary M Kupfer; Siri Atma W Greeley; Rosa Bacchetta; Eric Meffre; Maria Grazia Roncarolo; Neil Romberg; Kevan C Herold; Antoni Ribas; Manuel D Leonetti; Alexander Marson
Journal: Nature Date: 2018-07-11 Impact factor: 49.962

Review 10. Engineering CAR-T Cells for Next-Generation Cancer Therapy.

Authors: Mihe Hong; Justin D Clubb; Yvonne Y Chen
Journal: Cancer Cell Date: 2020-07-30 Impact factor: 31.743

1 in total

1. HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8⁺ T-cell infiltration into tumors.

Authors: Lei Guan; Bin Wu; Ting Li; Lynn A Beer; Gaurav Sharma; Mingyue Li; Chin Nien Lee; Shujing Liu; Changsong Yang; Lili Huang; Dennie T Frederick; Genevieve M Boland; Guangcan Shao; Tatyana M Svitkina; Kathy Q Cai; Fangping Chen; Meng-Qiu Dong; Gordon B Mills; Lynn M Schuchter; Giorgos C Karakousis; Tara C Mitchell; Keith T Flaherty; David W Speicher; Youhai H Chen; Meenhard Herlyn; Ravi K Amaravadi; Xiaowei Xu; Wei Guo
Journal: Nat Commun Date: 2022-07-14 Impact factor: 17.694

1 in total