Literature DB >> 33810908

Race, pain, and opioids among patients with chronic pain in a safety-net health system.

Nimah Haq1, Vanessa M McMahan2, Andrea Torres2, Glenn-Milo Santos3, Kelly Knight4, Margot Kushel4, Phillip O Coffin3.   

Abstract

BACKGROUND: Recent changes in opioid prescribing practices in the US may exacerbate disparities in opioid access among Black compared to White patients.
METHODS: To evaluate racial disparities in opioid prescribing and stewardship, we used baseline data collected from 2017 to 2019 for a longitudinal cohort of patients with chronic non-cancer pain and a history of illicit substance use. Sociodemographic characteristics, pain, psychological distress, substance use, and opioid prescription practices were compared between Black and White participants. We conducted multivariable logistic regression with race as the outcome. We also compared yellow flag events (opioid-related emergency department visits, illicit substances on urine drug screens, provider-documentation of concerning behaviors) by race.
RESULTS: Over half of participants analyzed were Black (57%) and the remainder White (43%). Participants with worse average pain in the past three months (adjusted odds ratio [AOR]:1.29, 95%CI:1.08-1.55, p = 0.006) had higher odds of being Black. Past-year injection drug use (AOR:0.39, 95%CI:0.16-0.94, p = 0.04) and a higher past-year maximum opioid dose (AOR per 10 morphine milligram equivalents (MME):0.99, 95%CI:0.98-1.00, p = 0.006) were associated with lower odds of being Black. We found no differences by race in the use of opioid stewardship measures or discontinuation of opioids based on yellow flag events.
CONCLUSION: Lower past-year maximum MME dose, despite higher average pain and less injection drug use, may represent bias away from prescribing opioids for chronic pain among Black patients. This could be due to unmeasured implicit provider bias or patient-level factors (e.g., utilizing non-opioid pain coping strategies or being less likely to request additional opioids).
Copyright © 2021 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Chronic pain; Opioids; Racial disparity; Substance use

Mesh:

Substances:

Year:  2021        PMID: 33810908      PMCID: PMC8687128          DOI: 10.1016/j.drugalcdep.2021.108671

Source DB:  PubMed          Journal:  Drug Alcohol Depend        ISSN: 0376-8716            Impact factor:   4.492


  22 in total

1.  Human experimental pain models 2: the cold pressor model.

Authors:  James G Modir; Mark S Wallace
Journal:  Methods Mol Biol       Date:  2010

2.  The interaction of patient race, provider bias, and clinical ambiguity on pain management decisions.

Authors:  Adam T Hirsh; Nicole A Hollingshead; Leslie Ashburn-Nardo; Kurt Kroenke
Journal:  J Pain       Date:  2015-03-28       Impact factor: 5.820

Review 3.  Understanding the micro and macro politics of health: Inequalities, intersectionality & institutions - A research agenda.

Authors:  Anna Gkiouleka; Tim Huijts; Jason Beckfield; Clare Bambra
Journal:  Soc Sci Med       Date:  2018-01-28       Impact factor: 4.634

Review 4.  A Systematic Review of the Impact of Physician Implicit Racial Bias on Clinical Decision Making.

Authors:  Erin Dehon; Nicole Weiss; Jonathan Jones; Whitney Faulconer; Elizabeth Hinton; Sarah Sterling
Journal:  Acad Emerg Med       Date:  2017-06-19       Impact factor: 3.451

5.  A synthesis of oral morphine equivalents (OME) for opioid utilisation studies.

Authors:  Suzanne Nielsen; Louisa Degenhardt; Bianca Hoban; Natasa Gisev
Journal:  Pharmacoepidemiol Drug Saf       Date:  2015-12-22       Impact factor: 2.890

6.  Opioid medication discontinuation and risk of adverse opioid-related health care events.

Authors:  Tami L Mark; William Parish
Journal:  J Subst Abuse Treat       Date:  2019-05-05

7.  Racial disparities in discontinuation of long-term opioid therapy following illicit drug use among black and white patients.

Authors:  Julie R Gaither; Kirsha Gordon; Stephen Crystal; E Jennifer Edelman; Robert D Kerns; Amy C Justice; David A Fiellin; William C Becker
Journal:  Drug Alcohol Depend       Date:  2018-08-06       Impact factor: 4.492

Review 8.  Differences in Pain Coping Between Black and White Americans: A Meta-Analysis.

Authors:  Samantha M Meints; Megan M Miller; Adam T Hirsh
Journal:  J Pain       Date:  2016-01-12       Impact factor: 5.820

Review 9.  Physicians and implicit bias: how doctors may unwittingly perpetuate health care disparities.

Authors:  Elizabeth N Chapman; Anna Kaatz; Molly Carnes
Journal:  J Gen Intern Med       Date:  2013-04-11       Impact factor: 5.128

10.  Clinical Effectiveness of Decision Support for Prescribing Opioids for Chronic Noncancer Pain: A Prospective Cohort Study.

Authors:  Eboni G Price-Haywood; Jeffrey Burton; Todd Burstain; Jewel Harden-Barrios; John Lefante; Lizheng Shi; Robert N Jamison; Alessandra Bazzano; Lydia Bazzano
Journal:  Value Health       Date:  2019-11-22       Impact factor: 5.725

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  2 in total

1.  Geographic Variation in the Use of Gabapentinoids and Opioids for Pain in a Commercially Insured Adult Population in the United States.

Authors:  Danni Zhao; Jonggyu Baek; Anne L Hume; Emily A McPhillips; Kate L Lapane
Journal:  J Pain Res       Date:  2022-02-11       Impact factor: 3.133

2.  Diversity inclusion in United States opioid pharmacological treatment trials: A systematic review.

Authors:  Tessa Nalven; Nichea S Spillane; Melissa R Schick; Lisa L Weyandt
Journal:  Exp Clin Psychopharmacol       Date:  2021-07-05       Impact factor: 3.492

  2 in total

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