Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Rho Family GTPases in Cancer.

Literature DB >> 33809395

Rho Family GTPases in Cancer.

Abstract

This Special Issue containing seminal contributions from international experts highlights the current understanding of Rho GTPases in cancer, with an emphasis on recognizing their central importance as critical targets for cancer therapy and for chemosensitization of current therapeutic strategies [...].

Entities: CellLine Chemical Disease Gene Species

Year: 2021 PMID： 33809395 PMCID： PMC7998900 DOI： 10.3390/cancers13061271

Source DB: PubMed Journal: Cancers (Basel) ISSN： 2072-6694 Impact factor: 6.639

10 in total

1. RAC1B Suppresses TGF-β-Dependent Chemokinesis and Growth Inhibition through an Autoregulatory Feed-Forward Loop Involving PAR2 and ALK5.

Authors: Hannah Otterbein; Koichiro Mihara; Morley D Hollenberg; Hendrik Lehnert; David Witte; Hendrik Ungefroren
Journal: Cancers (Basel) Date: 2019-08-20 Impact factor: 6.639

Review 2. MicroRNA Regulation of the Small Rho GTPase Regulators-Complexities and Opportunities in Targeting Cancer Metastasis.

Authors: Brock A Humphries; Zhishan Wang; Chengfeng Yang
Journal: Cancers (Basel) Date: 2020-04-28 Impact factor: 6.639

3. Drug Vulnerabilities and Disease Prognosis Linked to the Stem Cell-Like Gene Expression Program Triggered by the RHO GTPase Activator VAV2 in Hyperplastic Keratinocytes and Head and Neck Cancer.

Authors: Luis Francisco Lorenzo-Martín; Mauricio Menacho-Márquez; Xosé R Bustelo
Journal: Cancers (Basel) Date: 2020-09-03 Impact factor: 6.575

Rho Family GTPases in Cancer.

1. RAC1B Suppresses TGF-β-Dependent Chemokinesis and Growth Inhibition through an Autoregulatory Feed-Forward Loop Involving PAR2 and ALK5.

Review 2. MicroRNA Regulation of the Small Rho GTPase Regulators-Complexities and Opportunities in Targeting Cancer Metastasis.

3. Drug Vulnerabilities and Disease Prognosis Linked to the Stem Cell-Like Gene Expression Program Triggered by the RHO GTPase Activator VAV2 in Hyperplastic Keratinocytes and Head and Neck Cancer.

Review 4. Active RAC1 Promotes Tumorigenic Phenotypes and Therapy Resistance in Solid Tumors.

5. RAC1B Induces SMAD7 via USP26 to Suppress TGFβ1-Dependent Cell Migration in Mesenchymal-Subtype Carcinoma Cells.

Review 6. Dysregulation of Rho GTPases in Human Cancers.

7. P-REX1-Independent, Calcium-Dependent RAC1 Hyperactivation in Prostate Cancer.

Review 8. Rac1 Signaling: From Intestinal Homeostasis to Colorectal Cancer Metastasis.

9. Inhibition of Rho-Associated Kinase Suppresses Medulloblastoma Growth.