| Literature DB >> 33806624 |
Alessio Danilo Inchingolo1, Angelo Michele Inchingolo1, Ioana Roxana Bordea2, Giuseppina Malcangi1, Edit Xhajanka3, Antonio Scarano4, Felice Lorusso4, Marco Farronato5, Gianluca Martino Tartaglia5, Ciro Gargiulo Isacco1,6,7, Grazia Marinelli1, Maria Teresa D'Oria1,8, Denisa Hazballa1,9, Luigi Santacroce1, Andrea Ballini10,11, Maria Contaldo12, Francesco Inchingolo1, Gianna Dipalma1.
Abstract
The SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a high-risk viral agent involved in the recent pandemic stated worldwide by the World Health Organization. The infection is correlated to a severe systemic and respiratory disease in many cases, which is clinically treated with a multi-drug pharmacological approach. The purpose of this investigation was to evaluate through a literature overview the effect of adjuvant therapies and supplements for the SARS-CoV-2 infection. The research has analyzed the advantage of the EK1C4, by also assessing the studies on the resveratrol, vitamin D, and melatonin as adjuvant supplements for long hauler patients' prognosis. The evaluated substances reported important benefits for the improvement of the immune system and as a potential inhibitor molecules against SARS-CoV-2, highlighting the use of sartans as therapy. The adjuvant supplements seem to create an advantage for the healing of the long hauler patients affected by chronic symptoms of constant chest and heart pain, intestinal disorders, headache, difficulty concentrating, memory loss, and tachycardia.Entities:
Keywords: COVID-19; SARS-CoV-2; cytokine storm syndrome; endovir stop spray; furin; microbiome; oral mucosa; pandemics; resveratrol; vaccines
Year: 2021 PMID: 33806624 PMCID: PMC7999785 DOI: 10.3390/microorganisms9030525
Source DB: PubMed Journal: Microorganisms ISSN: 2076-2607