| Literature DB >> 3380338 |
O Gout1, A Gansmuller, N Baumann, M Gumpel.
Abstract
Fragments of normal newborn mouse central nervous system (CNS) were transplanted into the spinal cord of adult shiverer mice at distance of 1, 2 or 3 intervertebral spaces from a lysolecithin-induced demyelinating lesion. Remyelination by grafted oligodendrocytes was observed by electron microscopy (EM). This result showed the capability of grafted oligodendrocytes or precursor cells to migrate to a demyelinated lesion and to remyelinate naked axons in an adult host, even in presence of host spontaneous remyelination.Entities:
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Year: 1988 PMID： 3380338 DOI： 10.1016/0304-3940(88)90169-3
Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046