Alesandra Florescu1, Vlad Pădureanu2, Dan Nicolae Florescu3, Anca Bobircă4, Lucian-Mihai Florescu5, Ana-Maria Bumbea6, Rodica Pădureanu7, Anca Emanuela Mușetescu8. 1. Department of Rheumatology, Emergency Clinical County Hospital of Craiova, 200642 Craiova, Romania. 2. Department of Internal Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania. 3. Department of Gastroenterology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania. 4. Department of Rheumatology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania. 5. Department of Radiology and Medical Imaging, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania. 6. Department of Rehabilitation Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania. 7. Department of Internal Medicine, Emergency Clinical County Hospital of Craiova, 200642 Craiova, Romania. 8. Department of Rheumatology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Abstract
INTRODUCTION: Ankylosing spondylitis (AS) is a chronic inflammatory disease, part of the spondyloarthritis (SpA) group, characterized by axial (spine and sacroiliac joints), entheseal, and peripheral joint involvement, which is frequently associated with extra-articular manifestations. MATERIAL AND METHODS: The study included a number of 30 patients diagnosed with AS according to the New York modified criteria, with history of entheseal pain, hospitalized between 2016-2018 in the Department of Rheumatology of the Emergency County Hospital of Craiova. RESULTS: Regarding the Belgrade Ultrasound Enthesitis Score (BUSES) score and the disease activity calculated using the Ankylosing Spondylitis Disease Activity Score (ASDAS), they did not show a statistically significant association (p = 0.738). Additionally, BUSES did not have a statistically significant association with the disease activity quantified by the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) score (p = 0.094). The Spondyloarthritis Research Consortium of Canada Enthesitis Index (SPARCC) clinical score was not statistically associated with ASDAS (p = 0.434) nor with BASDAI (p = 0.130). The SPARCC clinical score and the BUSES ultrasound score were statistically significantly associated, registering a value of p = 0.018. CONCLUSIONS: Our study proved a significant correlation between SPARCC and BUSES, although in literature the evidence is contrasting.
INTRODUCTION:Ankylosing spondylitis (AS) is a chronic inflammatory disease, part of the spondyloarthritis (SpA) group, characterized by axial (spine and sacroiliac joints), entheseal, and peripheral joint involvement, which is frequently associated with extra-articular manifestations. MATERIAL AND METHODS: The study included a number of 30 patients diagnosed with AS according to the New York modified criteria, with history of entheseal pain, hospitalized between 2016-2018 in the Department of Rheumatology of the Emergency County Hospital of Craiova. RESULTS: Regarding the Belgrade Ultrasound Enthesitis Score (BUSES) score and the disease activity calculated using the Ankylosing Spondylitis Disease Activity Score (ASDAS), they did not show a statistically significant association (p = 0.738). Additionally, BUSES did not have a statistically significant association with the disease activity quantified by the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) score (p = 0.094). The Spondyloarthritis Research Consortium of Canada Enthesitis Index (SPARCC) clinical score was not statistically associated with ASDAS (p = 0.434) nor with BASDAI (p = 0.130). The SPARCC clinical score and the BUSES ultrasound score were statistically significantly associated, registering a value of p = 0.018. CONCLUSIONS: Our study proved a significant correlation between SPARCC and BUSES, although in literature the evidence is contrasting.
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