Literature DB >> 33802211

Non-Albumin Proteinuria (NAP) as a Complementary Marker for Diabetic Kidney Disease (DKD).

Jaehyun Bae1, Young Jun Won1, Byung-Wan Lee2.   

Abstract

Diabetic kidney disease (DKD) is one of the most common forms of chronic kidney disease. Its pathogenic mechanism is complex, and it can affect entire structures of the kidney. However, conventional approaches to early stage DKD have focused on changes to the glomerulus. Current standard screening tools for DKD, albuminuria, and estimated glomerular filtration rate are insufficient to reflect early tubular injury. Therefore, many tubular biomarkers have been suggested. Non-albumin proteinuria (NAP) contains a wide range of tubular biomarkers and is convenient to measure. We reviewed the clinical meanings of NAP and its significance as a marker for early stage DKD.

Entities:  

Keywords:  diabetic kidney disease; non-albumin proteinuria; tubular injury

Year:  2021        PMID： 33802211      PMCID： PMC7998887          DOI： 10.3390/life11030224

Source DB:  PubMed          Journal:  Life (Basel)        ISSN： 2075-1729


  85 in total

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Authors:  Jean-Michel Halimi; Buchler Matthias; Azmi Al-Najjar; Inass Laouad; Valérie Chatelet; Jean-Frédéric Marlière; Hubert Nivet; Yvon Lebranchu
Journal:  Am J Transplant       Date:  2007-10-19       Impact factor: 8.086

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Journal:  Diabetes Obes Metab       Date:  2018-04-23       Impact factor: 6.577

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Journal:  Sci Rep       Date:  2018-04-30       Impact factor: 4.379
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