Literature DB >> 33800961

In the Age of Viral Pandemic, Can Ingredients Inspired by Human Milk and Infant Nutrition Be Repurposed to Support the Immune System?

Lauren R Brink1, Maciej Chichlowski1, Nitida Pastor1, Athmaram Thimmasandra Narayanappa2, Neil Shah3,4.   

Abstract

In 2020, with the advent of a pandemic touching all aspects of global life, there is a renewed interest in nutrition solutions to support the immune system. Infants are vulnerable to infection and breastfeeding has been demonstrated to provide protection. As such, human milk is a great model for sources of functional nutrition ingredients, which may play direct roles in protection against viral diseases. This review aims to summarize the literature around human milk (lactoferrin, milk fat globule membrane, osteopontin, glycerol monolaurate and human milk oligosaccharides) and infant nutrition (polyunsaturated fatty acids, probiotics and postbiotics) inspired ingredients for support against viral infections and the immune system more broadly. We believe that the application of these ingredients can span across all life stages and thus apply to both pediatric and adult nutrition. We highlight the opportunities for further research in this field to help provide tangible nutrition solutions to support one's immune system and fight against infections.

Entities:  

Keywords:  anti-viral; glycerol monolaurate; human milk oligosaccharides; infant nutrition; lactoferrin; milk fat globule membrane; osteopontin; polyunsaturated fatty acids; postbiotics; probiotics

Year:  2021        PMID: 33800961      PMCID: PMC7999376          DOI: 10.3390/nu13030870

Source DB:  PubMed          Journal:  Nutrients        ISSN: 2072-6643            Impact factor:   5.717


  249 in total

1.  Effect of antimicrobial factors in human milk on rhinoviruses and milk-borne cytomegalovirus in vitro.

Authors:  N M Clarke; J T May
Journal:  J Med Microbiol       Date:  2000-08       Impact factor: 2.472

2.  Effects of lactoferrin-containing formula in the prevention of enterovirus and rotavirus infection and impact on serum cytokine levels: a randomized trial.

Authors:  Meng-Hsiu Yen; Cheng-Hsun Chiu; Yhu-Chering Huang; Tzou-Yien Lin
Journal:  Chang Gung Med J       Date:  2011 Jul-Aug

Review 3.  Potential lactoferrin activity against pathogenic viruses.

Authors:  Elrashdy M Redwan; Vladimir N Uversky; Esmail M El-Fakharany; Hussein Al-Mehdar
Journal:  C R Biol       Date:  2014-09-22       Impact factor: 1.583

4.  Immunomodulatory and prophylactic effects of Bifidobacterium bifidum probiotic strain on influenza infection in mice.

Authors:  Mehran Mahooti; Elahe Abdolalipour; Ali Salehzadeh; Seyed Reza Mohebbi; Ali Gorji; Amir Ghaemi
Journal:  World J Microbiol Biotechnol       Date:  2019-06-03       Impact factor: 3.312

5.  Effects of lactoferrin on infectious diseases in Japanese summer: A randomized, double-blinded, placebo-controlled trial.

Authors:  Hirotsugu Oda; Hiroyuki Wakabayashi; Miyuki Tanaka; Koji Yamauchi; Chihiro Sugita; Hiroki Yoshida; Fumiaki Abe; Tohru Sonoda; Masahiko Kurokawa
Journal:  J Microbiol Immunol Infect       Date:  2020-02-26       Impact factor: 4.399

6.  Bioavailability of a Novel Form of Microencapsulated Bovine Lactoferrin and Its Effect on Inflammatory Markers and the Gut Microbiome: A Pilot Study.

Authors:  Clare Dix; Olivia Wright
Journal:  Nutrients       Date:  2018-08-17       Impact factor: 5.717

Review 7.  Compositional Dynamics of the Milk Fat Globule and Its Role in Infant Development.

Authors:  Hanna Lee; Emily Padhi; Yu Hasegawa; Jules Larke; Mariana Parenti; Aidong Wang; Olle Hernell; Bo Lönnerdal; Carolyn Slupsky
Journal:  Front Pediatr       Date:  2018-10-24       Impact factor: 3.418

Review 8.  Lactoferrin a multiple bioactive protein: an overview.

Authors:  Isui Abril García-Montoya; Tania Siqueiros Cendón; Sigifredo Arévalo-Gallegos; Quintín Rascón-Cruz
Journal:  Biochim Biophys Acta       Date:  2011-06-25

Review 9.  Scientific research progress of COVID-19/SARS-CoV-2 in the first five months.

Authors:  Hua Li; Zhe Liu; Junbo Ge
Journal:  J Cell Mol Med       Date:  2020-05-07       Impact factor: 5.310

Review 10.  Nutrition and the Immune System: A Complicated Tango.

Authors:  Carina Venter; Stefanie Eyerich; Tara Sarin; Kevin C Klatt
Journal:  Nutrients       Date:  2020-03-19       Impact factor: 5.717

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  3 in total

Review 1.  Overview of Breastfeeding Under COVID-19 Pandemic.

Authors:  Zehan Pang; Ruolan Hu; Lili Tian; Fuxing Lou; Yangzhen Chen; Shuqi Wang; Shiting He; Shaozhou Zhu; Xiaoping An; Lihua Song; Feitong Liu; Yigang Tong; Huahao Fan
Journal:  Front Immunol       Date:  2022-05-31       Impact factor: 8.786

2.  Glycerol monolaurate ameliorates DSS-induced acute colitis by inhibiting infiltration of Th17, neutrophils, macrophages and altering the gut microbiota.

Authors:  Ke-Jie He; Jia-Hui Dong; Xiao-Mei Ouyang; Ya-Ni Huo; Xiao-Shen Cheng; Ying Lin; Yue Li; Guoyu Gong; Jingjing Liu; Jian-Lin Ren; Bayasi Guleng
Journal:  Front Nutr       Date:  2022-08-12

Review 3.  Understanding Rhinovirus Circulation and Impact on Illness.

Authors:  Camille Esneau; Alexandra Cate Duff; Nathan W Bartlett
Journal:  Viruses       Date:  2022-01-13       Impact factor: 5.048

  3 in total

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