Literature DB >> 33800896

SEAHIR: A Specialized Compartmental Model for COVID-19.

Alexandros Leontitsis1, Abiola Senok2, Alawi Alsheikh-Ali2, Younus Al Nasser1, Tom Loney2, Aamena Alshamsi1.   

Abstract

The SEIR (Susceptible-Exposed-Infected-Removed) model is widely used in epidemiology to mathematically model the spread of infectious diseases with incubation periods. However, the SEIR model prototype is generic and not able to capture the unique nature of a novel viral pandemic such as SARS-CoV-2. We have developed and tested a specialized version of the SEIR model, called SEAHIR (Susceptible-Exposed-Asymptomatic-Hospitalized-Isolated-Removed) model. This proposed model is able to capture the unique dynamics of the COVID-19 outbreak including further dividing the Infected compartment into: (1) "Asymptomatic", (2) "Isolated" and (3) "Hospitalized" to delineate the transmission specifics of each compartment and forecast healthcare requirements. The model also takes into consideration the impact of non-pharmaceutical interventions such as physical distancing and different testing strategies on the number of confirmed cases. We used a publicly available dataset from the United Arab Emirates (UAE) as a case study to optimize the main parameters of the model and benchmarked it against the historical number of cases. The SEAHIR model was used by decision-makers in Dubai's COVID-19 Command and Control Center to make timely decisions on developing testing strategies, increasing healthcare capacity, and implementing interventions to contain the spread of the virus. The novel six-compartment SEAHIR model could be utilized by decision-makers and researchers in other countries for current or future pandemics.

Entities:  

Keywords:  COVID-19; Erlang distribution; SARS-CoV-2; SEIR; compartmental models; predictive modelling

Mesh:

Year:  2021        PMID: 33800896      PMCID: PMC7967501          DOI: 10.3390/ijerph18052667

Source DB:  PubMed          Journal:  Int J Environ Res Public Health        ISSN: 1660-4601            Impact factor:   3.390


  13 in total

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Authors:  Mohammed Uddin; Farah Mustafa; Tahir A Rizvi; Tom Loney; Hanan Al Suwaidi; Ahmed H Hassan Al-Marzouqi; Afaf Kamal Eldin; Nabeel Alsabeeha; Thomas E Adrian; Cesare Stefanini; Norbert Nowotny; Alawi Alsheikh-Ali; Abiola C Senok
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  6 in total

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