Literature DB >> 33799967

Neuroinflammation and Hypothalamo-Pituitary Dysfunction: Focus of Traumatic Brain Injury.

Chiara Mele1, Valeria Pingue2, Marina Caputo3,4, Marco Zavattaro4,5, Loredana Pagano5, Flavia Prodam3,4, Antonio Nardone1,2, Gianluca Aimaretti4,6, Paolo Marzullo4,6,7.   

Abstract

The incidence of traumatic brain injury (TBI) has increased over the last years with an important impact on public health. Many preclinical and clinical studies identified multiple and heterogeneous TBI-related pathophysiological mechanisms that are responsible for functional, cognitive, and behavioral alterations. Recent evidence has suggested that post-TBI neuroinflammation is responsible for several long-term clinical consequences, including hypopituitarism. This review aims to summarize current evidence on TBI-induced neuroinflammation and its potential role in determining hypothalamic-pituitary dysfunctions.

Entities:  

Keywords:  hypopituitarism; neuroinflammation; traumatic brain injury

Mesh:

Substances:

Year:  2021        PMID: 33799967      PMCID: PMC7961958          DOI: 10.3390/ijms22052686

Source DB:  PubMed          Journal:  Int J Mol Sci        ISSN: 1422-0067            Impact factor:   5.923


  202 in total

1.  Autoreactive antibodies against neurons and basal lamina found in serum following experimental brain contusion in rats.

Authors:  S Rudehill; S Muhallab; A Wennersten; C von Gertten; F Al Nimer; A C Sandberg-Nordqvist; S Holmin; T Mathiesen
Journal:  Acta Neurochir (Wien)       Date:  2005-12-20       Impact factor: 2.216

Review 2.  T cells in multiple sclerosis and experimental autoimmune encephalomyelitis.

Authors:  J M Fletcher; S J Lalor; C M Sweeney; N Tubridy; K H G Mills
Journal:  Clin Exp Immunol       Date:  2010-10       Impact factor: 4.330

3.  A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury.

Authors:  John R Lynch; Haichen Wang; Brian Mace; Stephen Leinenweber; David S Warner; Ellen R Bennett; Michael P Vitek; Suzanne McKenna; Daniel T Laskowitz
Journal:  Exp Neurol       Date:  2005-03       Impact factor: 5.330

Review 4.  Cognitive sequelae of traumatic brain injury.

Authors:  Amanda R Rabinowitz; Harvey S Levin
Journal:  Psychiatr Clin North Am       Date:  2014-01-14

5.  Anterior pituitary dysfunction in survivors of traumatic brain injury.

Authors:  Amar Agha; Bairbre Rogers; Mark Sherlock; Patrick O'Kelly; William Tormey; Jack Phillips; Christopher J Thompson
Journal:  J Clin Endocrinol Metab       Date:  2004-10       Impact factor: 5.958

6.  Dynamic pituitary hormones change after traumatic brain injury.

Authors:  Ping Zheng; Bin He; Wusong Tong
Journal:  Neurol India       Date:  2014 May-Jun       Impact factor: 2.117

7.  Novel Molecular Insights into Classical and Alternative Activation States of Microglia as Revealed by Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)-based Proteomics.

Authors:  Harris Bell-Temin; Ashley E Culver-Cochran; Dale Chaput; Christina M Carlson; Melanie Kuehl; Brant R Burkhardt; Paula C Bickford; Bin Liu; Stanley M Stevens
Journal:  Mol Cell Proteomics       Date:  2015-09-30       Impact factor: 5.911

8.  Blood-Brain Barrier Disruption Is an Early Event That May Persist for Many Years After Traumatic Brain Injury in Humans.

Authors:  Jennifer R Hay; Victoria E Johnson; Adam M H Young; Douglas H Smith; William Stewart
Journal:  J Neuropathol Exp Neurol       Date:  2015-12       Impact factor: 3.148

9.  Time-dependent effects of CX3CR1 in a mouse model of mild traumatic brain injury.

Authors:  Heidi Y Febinger; Hannah E Thomasy; Maria N Pavlova; Kristyn M Ringgold; Paulien R Barf; Amrita M George; Jenna N Grillo; Adam D Bachstetter; Jenny A Garcia; Astrid E Cardona; Mark R Opp; Carmelina Gemma
Journal:  J Neuroinflammation       Date:  2015-09-02       Impact factor: 8.322

Review 10.  Brain-Immune Interactions and Neuroinflammation After Traumatic Brain Injury.

Authors:  Virginie Dinet; Klaus G Petry; Jerome Badaut
Journal:  Front Neurosci       Date:  2019-11-12       Impact factor: 4.677

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  2 in total

Review 1.  Traumatic Brain Injury as a Potential Risk Factor for Diabetes Mellitus in the Veteran Population.

Authors:  Sepehr Saberian; Christian M Mustroph; Fahim Atif; Don Stein; Seema Yousuf
Journal:  Cureus       Date:  2022-07-26

2.  Thyrotropic Axis and Disorders of Consciousness in Acquired Brain Injury: A Potential Intriguing Association?

Authors:  Chiara Mele; Antonio De Tanti; Sergio Bagnato; Lucia Francesca Lucca; Donatella Saviola; Anna Estraneo; Pasquale Moretta; Laura Marcuccio; Bernardo Lanzillo; Gianluca Aimaretti; Antonio Nardone; Paolo Marzullo; Valeria Pingue
Journal:  Front Endocrinol (Lausanne)       Date:  2022-07-07       Impact factor: 6.055

  2 in total

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