| Literature DB >> 33799842 |
Alexander S Jureka1, Caroline G Williams1, Christopher F Basler1.
Abstract
The ongoing SARS-CoV-2 pandemic has resulted in an increased need for technologies capable of efficiently disinfecting public spaces as well as personal protective equipment. UV light disinfection is a well-established method for inactivating respiratory viruses. Here, we have determined that broad-spectrum, pulsed UV light is effective at inactivating SARS-CoV-2 on multiple surfaces in vitro. For hard, non-porous surfaces, we observed that SARS-CoV-2 was inactivated to undetectable levels on plastic and glass with a UV dose of 34.9 mJ/cm2 and stainless steel with a dose of 52.5 mJ/cm2. We also observed that broad-spectrum, pulsed UV light is effective at reducing SARS-CoV-2 on N95 respirator material to undetectable levels with a dose of 103 mJ/cm2. We included UV dosimeter cards that provide a colorimetric readout of UV dose and demonstrated their utility as a means to confirm desired levels of exposure were reached. Together, the results presented here demonstrate that broad-spectrum, pulsed UV light is an effective technology for the in vitro inactivation of SARS-CoV-2 on multiple surfaces.Entities:
Keywords: COVID-19; SARS-CoV-2; coronavirus; inactivation; ultraviolet
Mesh:
Year: 2021 PMID: 33799842 PMCID: PMC7998866 DOI: 10.3390/v13030460
Source DB: PubMed Journal: Viruses ISSN: 1999-4915 Impact factor: 5.048