| Literature DB >> 33798571 |
Loredana Elena Nita1, Aurica P Chiriac2, Alina Ghilan2, Alina Gabriela Rusu2, Nita Tudorachi2, Daniel Timpu2.
Abstract
Alginate hydrogels are extremely versatile and flexible biomaterials, with an enormous potential for bio-applications use. Their similarity with extracellular matrix is a key factor in their performance for cell and tissue regeneration. In this study superabsorbent high porous hydrogels based on sodium alginate physical crosslinked with a natural crosslinker compound namely phytic acid were prepared and evaluated from the viewpoint of their specific properties. The resulting hydrogels obtained with different ratios between alginate and phytic acid were characterized by Fourier transform infrared spectroscopy technique, scanning electron microscopy, XRD measurements, swelling tests in physiological environment, and thermal analysis by using a simultaneous TG/FT-IR/MS system. There are put into evidence the differences in physico-chemical properties of the hydrogels in relation with their composition, which endows them tunable properties and versatility.Entities:
Keywords: Alginate; Bio-crosslinker; Hydrogel
Year: 2021 PMID: 33798571 DOI: 10.1016/j.ijbiomac.2021.03.164
Source DB: PubMed Journal: Int J Biol Macromol ISSN: 0141-8130 Impact factor: 6.953