Fikret Poyraz Çökmüş1, Kadir Aşçibaşi2, Didem SüCüllüoğlu Dikici1, Emine Özge Çöldür3, Emin Avci4, Ömer Aydemir4. 1. Manisa Mental Health and Disease Hospital, Psychiatry Clinic, Manisa, Turkey. 2. Tepecik Training and Research Hospital, Department of Psychiatry, İzmir, Turkey. 3. Kuşadası State Hospital, Psychiatry Clinic, Aydın, Turkey. 4. Manisa Celal Bayar University Hospital, Department of Psychiatry, Manisa, Turkey.
Abstract
INTRODUCTION: Even though an increase in the number of hospital admissions for manic and depressive periods at certain times of the year is reported in bipolar disorder (BD), mood symptoms do not show a seasonal variation. We aimed to find out the possible causes of increased hospital admissions of BD patients in certain periods of the year. METHODS: The study was carried out in four centers in Turkey. The patient group consisted of 41 persons with a diagnosis of BD in remission. The healthy control (HC) group consists of 37 persons. The selected evaluation times are fall equinox (September 23), spring equinox (March 21), summer solstice (June 21) and winter solstice (December 21). For mood symptoms, Hamilton Depression Rating Scale and Young Mania Rating Scale; for functioning Functioning Assessment Short Test; for neurocognition Stroop Test (ST) and Rey Auditory Verbal Learning Test (RAVLT), for biological rhythm Biological Rhythms Interview of Assessment in Neuropsychiatry, and Seasonal Pattern Assessment Questionnaire were used. RESULTS: In terms of mood symptoms no seasonal variation was found. Across all four periods of assessment of BD group, statistically significant variation was only observed in the instant recall, learning and recognition domains of RAVLT and word test and color test domains of ST; however, it was not sufficient to distinguish the BD group separating from the control group. CONCLUSIONS: In terms of mood symptoms, psychosocial functionality, biological rhythm, neurocognition, no seasonal variation was demonstrated that could distinguish the BD group from the HC group. Copyright:
INTRODUCTION: Even though an increase in the number of hospital admissions for manic and depressive periods at certain times of the year is reported in bipolar disorder (BD), mood symptoms do not show a seasonal variation. We aimed to find out the possible causes of increased hospital admissions of BD patients in certain periods of the year. METHODS: The study was carried out in four centers in Turkey. The patient group consisted of 41 persons with a diagnosis of BD in remission. The healthy control (HC) group consists of 37 persons. The selected evaluation times are fall equinox (September 23), spring equinox (March 21), summer solstice (June 21) and winter solstice (December 21). For mood symptoms, Hamilton Depression Rating Scale and Young Mania Rating Scale; for functioning Functioning Assessment Short Test; for neurocognition Stroop Test (ST) and Rey Auditory Verbal Learning Test (RAVLT), for biological rhythm Biological Rhythms Interview of Assessment in Neuropsychiatry, and Seasonal Pattern Assessment Questionnaire were used. RESULTS: In terms of mood symptoms no seasonal variation was found. Across all four periods of assessment of BD group, statistically significant variation was only observed in the instant recall, learning and recognition domains of RAVLT and word test and color test domains of ST; however, it was not sufficient to distinguish the BD group separating from the control group. CONCLUSIONS: In terms of mood symptoms, psychosocial functionality, biological rhythm, neurocognition, no seasonal variation was demonstrated that could distinguish the BD group from the HC group. Copyright:
Authors: Michael Bauer; Tasha Glenn; Paul Grof; Natalie L Rasgon; Wendy Marsh; Kemal Sagduyu; Martin Alda; Greg Murray; Danilo Quiroz; Yanni Malliaris; Johanna Sasse; Maximilian Pilhatsch; Peter C Whybrow Journal: J Affect Disord Date: 2008-12-16 Impact factor: 4.839