Literature DB >> 33792391

Treatment of COVID-19: a review of current and prospective pharmacotherapies.

Eleanor Quek1, Hasan Tahir2,3, Poornima Kumar4, Robert Hastings5, Rajeev Jha6.   

Abstract

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread and have grave health and socioeconomic consequences worldwide. Researchers have raced to understand the pathophysiological mechanisms underpinning the disease caused by SARS-CoV-2 so that effective therapeutic targets can be discovered. This review summarises the key pharmacotherapies that are being investigated for treatment of COVID-19, including antiviral, immunomodulator and anticoagulation strategies.

Entities:  

Keywords:  Anticoagulation; Antivirals; COVID-19; Immunomodulator

Mesh：

Substances：

Year:  2021        PMID： 33792391     DOI： 10.12968/hmed.2021.0112

Source DB:  PubMed          Journal:  Br J Hosp Med (Lond)        ISSN： 1750-8460            Impact factor:   0.825


  5 in total

Review 1.  Current Use of Baricitinib in COVID-19 Treatment and Its Future: An Updated Literature Review.

Authors:  Derma Dupuis; Kasinda Fritz; Emeka Ike; Oyinkansola Arogundade; Enoch O Adewara; Esther O Monday; Bolaji O Ayinde
Journal:  Cureus       Date:  2022-09-01

2.  Key Considerations for Phase 2 or 3 Clinical Study Design of Anti-Inflammatory Agent for COVID-19 Treatment.

Authors:  Yewon Park; Joo Young Na; Joo-Youn Cho; Jaeseong Oh; Su-Jin Rhee
Journal:  Front Pharmacol       Date:  2022-06-02       Impact factor: 5.988

Review 3.  Targeting the Ubiquitylation and ISGylation Machinery for the Treatment of COVID-19.

Authors:  George Vere; Md Rashadul Alam; Sam Farrar; Rachel Kealy; Benedikt M Kessler; Darragh P O'Brien; Adán Pinto-Fernández
Journal:  Biomolecules       Date:  2022-02-12

4.  Liposomal Formulation of a PLA2-Sensitive Phospholipid-Allocolchicinoid Conjugate: Stability and Activity Studies In Vitro.

Authors:  Maria K Kobanenko; Daria S Tretiakova; Ekaterina S Shchegravina; Nadezhda V Antipova; Ivan A Boldyrev; Alexey Yu Fedorov; Elena L Vodovozova; Natalia R Onishchenko
Journal:  Int J Mol Sci       Date:  2022-01-18       Impact factor: 5.923

5.  Effectiveness of Curcumin on Outcomes of Hospitalized COVID-19 Patients: A Systematic Review of Clinical Trials.

Authors:  Amir Vahedian-Azimi; Mitra Abbasifard; Farshid Rahimi-Bashar; Paul C Guest; Muhammed Majeed; Asadollah Mohammadi; Maciej Banach; Tannaz Jamialahmadi; Amirhossein Sahebkar
Journal:  Nutrients       Date:  2022-01-07       Impact factor: 5.717
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.