Literature DB >> 33791173

Frequency of Preoperative Localization Techniques of Parathyroid Adenoma at King Abdulaziz University Hospital, Saudi Arabia.

Hani Z Marzouki1, Mawaddah Abdulhaleem2, Linah Qasim3, Ahmad Aldajani4, Shaza Samargandy5, Amani Alhozali5, Faisal Zawawi1, Mazin Merdad1.   

Abstract

Background Accurate preoperative radiological localization of parathyroid pathologies paves the way to enable less invasive surgical procedures. Results on the accuracy of the different diagnostic measures are conflicting. Also, little is known about the most common location of parathyroid lesions. This paper aims to determine the most common location of parathyroid adenoma and evaluate the diagnostic performance of radiological modalities such as ultrasonography, sestamibi scintigraphy/single-photon emission computerized tomography (SPECT), magnetic resonance imaging (MRI), and computed tomography (CT) scan for the preoperative localization of parathyroid pathologies. Methods This is a retrospective study. Data were collected from patients who underwent total or partial parathyroidectomy at King Abdulaziz University Hospital between January 2000 and March 2020. The parathyroid adenoma site was detected preoperatively by a radiological method and confirmed postoperatively by the histopathology report. The performance of each preoperative localizing radiological method was evaluated based on the accuracy in localizing parathyroid pathology. Results A total of 73 patients were included in the analysis, with females being the most common gender in the study at 64%. Only complete data files were included and incomplete data files were excluded. The most frequent mode of detecting parathyroid adenoma was a sestamibi/SPECT scan (62.5%) followed by a CT scan (50%), ultrasound (34.6%), and MRI (25%). The most common location of a parathyroid adenoma was the left side. Conclusion Sestamibi/SPECT is a frequent radiological method for detecting the parathyroid lesion site as compared with CT, MRI, and ultrasonography.
Copyright © 2021, Marzouki et al.

Entities:  

Keywords:  accuracy; imaging; parathyroid; parathyroid pathology; preoperatively; radiological modalities

Year:  2021        PMID: 33791173      PMCID: PMC8001217          DOI: 10.7759/cureus.13550

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  24 in total

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Journal:  Radiology       Date:  1987-01       Impact factor: 11.105

Review 2.  Parathyroid localization, three-dimensional modeling, and percutaneous ablation techniques.

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Journal:  Endocrinol Metab Clin North Am       Date:  1989-09       Impact factor: 4.741

3.  One hundred consecutive minimally invasive parathyroid explorations.

Authors:  R Udelsman; P I Donovan; L J Sokoll
Journal:  Ann Surg       Date:  2000-09       Impact factor: 12.969

4.  Parathyroid glands: combination of (99m)Tc MIBI scintigraphy and US for demonstration of parathyroid glands and nodules.

Authors:  M L De Feo; S Colagrande; C Biagini; A Tonarelli; G Bisi; L Vaggelli; D Borrelli; P Cicchi; F Tonelli; A Amorosi; M Serio; M L Brandi
Journal:  Radiology       Date:  2000-02       Impact factor: 11.105

Review 5.  A systematic review of the diagnosis and treatment of primary hyperparathyroidism from 1995 to 2003.

Authors:  James M Ruda; Christopher S Hollenbeak; Brendan C Stack
Journal:  Otolaryngol Head Neck Surg       Date:  2005-03       Impact factor: 3.497

6.  Reoperative parathyroidectomy in the era of localization technology.

Authors:  L Rotstein; J Irish; P Gullane; M A Keller; K Sniderman
Journal:  Head Neck       Date:  1998-09       Impact factor: 3.147

7.  Prospective comparison of technetium-99m-sestamibi/iodine-123 radionuclide scan versus high-resolution ultrasonography for the preoperative localization of abnormal parathyroid glands in patients with previously unoperated primary hyperparathyroidism.

Authors:  A T Casas; G J Burke; A R Mansberger; J P Wei
Journal:  Am J Surg       Date:  1993-10       Impact factor: 2.565

8.  Parathyroid scintigraphy with 99mTc-MIBI and 123I subtraction: a comparison with magnetic resonance imaging and ultrasonography.

Authors:  H Wakamatsu; S Noguchi; H Yamashita; H Yamashita; S Tamura; S Jinnouchi; S Nagamachi; S Futami
Journal:  Nucl Med Commun       Date:  2003-07       Impact factor: 1.690

9.  Comparison among sonography, double-tracer subtraction scintigraphy, and double-phase scintigraphy in the detection of parathyroid lesions.

Authors:  S Mazzeo; D Caramella; R Lencioni; N Molea; A De Liperi; C Marcocci; P Miccoli; P Iacconi; G B Bossio; P Viacava; E Lazzeri; C Bartolozzi
Journal:  AJR Am J Roentgenol       Date:  1996-06       Impact factor: 3.959

10.  Parathyroid adenoma Localization.

Authors:  Shirzad Nasiri; Ahmadreza Soroush; Amir Pejman Hashemi; Anushiravan Hedayat; Kianoush Donboli; Farhad Mehrkhani
Journal:  Med J Islam Repub Iran       Date:  2012-08
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