Literature DB >> 3378456

Regional localization of the gene for thyroid peroxidase to human chromosome 2pter----p12.

J J de Vijlder1, C Dinsart, F Libert, A Geurts van Kessel, H Bikker, P A Bolhuis, G Vassart.   

Abstract

A 2.0-kb thyroid peroxidase cDNA of human origin was used as probe for Southern blot hybridization of genomic DNA from human somatic cells and human-rodent somatic cell hybrids. The results showed that the gene coding for human thyroid peroxidase is located on chromosome. 2. Further analysis of hybrids derived from Burkitt lymphoma cells carrying a (2;8)(p12;q24) translocation revealed that the gene maps to the region 2pter----p12.

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Year:  1988        PMID: 3378456     DOI: 10.1159/000132538

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN: 0301-0171


  6 in total

Review 1.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

2.  AcyI-RFLP in intron 8 of hTPO gene.

Authors:  G Rose; O Leone; C Giacchetto; G De Benedictis
Journal:  Nucleic Acids Res       Date:  1992-03-11       Impact factor: 16.971

Review 3.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

4.  Eco RI RFLP in the human thyroid peroxidase (TPO) gene on chromosome 2.

Authors:  H Bikker; P A Bolhuis; G Vassart; F Libert; G Massaro; J J de Vijlder
Journal:  Hum Genet       Date:  1989-04       Impact factor: 4.132

5.  Identification of a mutation in the coding sequence of the human thyroid peroxidase gene causing congenital goiter.

Authors:  M J Abramowicz; H M Targovnik; V Varela; P Cochaux; L Krawiec; M A Pisarev; F V Propato; G Juvenal; H A Chester; G Vassart
Journal:  J Clin Invest       Date:  1992-10       Impact factor: 14.808

6.  Clinical, Pathological, and Molecular Studies of Two Families with Iodide Organification Defect.

Authors:  Katia G. M. Rego; Ana Elisa C. Billerbeck; Hector M. Targovnik; Cecilia L. S. Santos; Maria G. Alkmin; Sonia Barbosa; Rosalinda Camargo; Geraldo Medeiros-Neto
Journal:  Endocr Pathol       Date:  1997       Impact factor: 3.943

  6 in total

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