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Literature DB >> 33783997

A CRISPR/CAS9-based strategy targets the personalized chimeric neosequence in fusion-driven cancer genome for precision medicine.

Wei Huang¹, Zhan-Cheng Zeng¹, Wen-Tao Wang¹, Yu-Meng Sun¹, Yue-Qin Chen¹, Xue-Qun Luo², Ke Fang¹.

Abstract

Entities: Chemical

Mesh：

Year: 2021 PMID： 33783997 PMCID： PMC7967915 DOI： 10.1002/ctm2.355

Source DB: PubMed Journal: Clin Transl Med ISSN： 2001-1326

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10 in total

Review 1. Targeting chromatin complexes in fusion protein-driven malignancies.

Authors: Gerard L Brien; Kimberly Stegmaier; Scott A Armstrong
Journal: Nat Rev Cancer Date: 2019-05 Impact factor: 60.716

Review 2. Pushing the limits of targeted therapy in chronic myeloid leukaemia.

Authors: Thomas O'Hare; Matthew S Zabriskie; Anna M Eiring; Michael W Deininger
Journal: Nat Rev Cancer Date: 2012-07-24 Impact factor: 60.716

3. "Off-Spotter": very fast and exhaustive enumeration of genomic lookalikes for designing CRISPR/Cas guide RNAs.

Authors: Venetia Pliatsika; Isidore Rigoutsos
Journal: Biol Direct Date: 2015-01-29 Impact factor: 4.540

4. Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease.

Authors: James E Dahlman; Omar O Abudayyeh; Julia Joung; Jonathan S Gootenberg; Feng Zhang; Silvana Konermann
Journal: Nat Biotechnol Date: 2015-11 Impact factor: 54.908

5. Analysis of protein-coding genetic variation in 60,706 humans.

Authors: Monkol Lek; Konrad J Karczewski; Eric V Minikel; Kaitlin E Samocha; Eric Banks; Timothy Fennell; Anne H O'Donnell-Luria; James S Ware; Andrew J Hill; Beryl B Cummings; Taru Tukiainen; Daniel P Birnbaum; Jack A Kosmicki; Laramie E Duncan; Karol Estrada; Fengmei Zhao; James Zou; Emma Pierce-Hoffman; Joanne Berghout; David N Cooper; Nicole Deflaux; Mark DePristo; Ron Do; Jason Flannick; Menachem Fromer; Laura Gauthier; Jackie Goldstein; Namrata Gupta; Daniel Howrigan; Adam Kiezun; Mitja I Kurki; Ami Levy Moonshine; Pradeep Natarajan; Lorena Orozco; Gina M Peloso; Ryan Poplin; Manuel A Rivas; Valentin Ruano-Rubio; Samuel A Rose; Douglas M Ruderfer; Khalid Shakir; Peter D Stenson; Christine Stevens; Brett P Thomas; Grace Tiao; Maria T Tusie-Luna; Ben Weisburd; Hong-Hee Won; Dongmei Yu; David M Altshuler; Diego Ardissino; Michael Boehnke; John Danesh; Stacey Donnelly; Roberto Elosua; Jose C Florez; Stacey B Gabriel; Gad Getz; Stephen J Glatt; Christina M Hultman; Sekar Kathiresan; Markku Laakso; Steven McCarroll; Mark I McCarthy; Dermot McGovern; Ruth McPherson; Benjamin M Neale; Aarno Palotie; Shaun M Purcell; Danish Saleheen; Jeremiah M Scharf; Pamela Sklar; Patrick F Sullivan; Jaakko Tuomilehto; Ming T Tsuang; Hugh C Watkins; James G Wilson; Mark J Daly; Daniel G MacArthur
Journal: Nature Date: 2016-08-18 Impact factor: 49.962

10. Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases.

Authors: Sangsu Bae; Jeongbin Park; Jin-Soo Kim
Journal: Bioinformatics Date: 2014-01-24 Impact factor: 6.937

10 in total

A CRISPR/CAS9-based strategy targets the personalized chimeric neosequence in fusion-driven cancer genome for precision medicine.

Review 1. Targeting chromatin complexes in fusion protein-driven malignancies.

Review 2. Pushing the limits of targeted therapy in chronic myeloid leukaemia.

3. "Off-Spotter": very fast and exhaustive enumeration of genomic lookalikes for designing CRISPR/Cas guide RNAs.

4. Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease.

5. Analysis of protein-coding genetic variation in 60,706 humans.

Review 6. Molecular mechanisms, off-target activities, and clinical potentials of genome editing systems.

Review 7. The clinical potential of gene editing as a tool to engineer cell-based therapeutics.

Review 8. Allele-specific genome targeting in the development of precision medicine.

9. High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity.

10. Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases.