Literature DB >> 33782725

The First Use of Human-Derived ADM in Prepectoral Direct-to-Implant Breast Reconstruction after Skin-Reducing Mastectomy.

Francesco Marongiu1, Nicolò Bertozzi2, Andrea Sibilio1, Daniela Tognali1, Matteo Mingozzi1, Annalisa Curcio1.   

Abstract

INTRODUCTION: Large and ptotic breasts always represented a great reconstructive challenge for plastic surgeons. In order to deal with these patients, we started performing Wise-pattern skin-reducing mastectomies (SRM) followed by direct-to-implant breast reconstructions (DTI-BR) in the prepectoral space where the implants were covered with the autologous adipo-dermal flap and a human acellular dermal matrix called MODA. MATERIALS AND
METHOD: We retrospectively reviewed all patients that underwent Wise-pattern SRM followed by MODA-assisted, prepectoral, DTI-BR between January 2017 and November 2019 at our Institution. Inclusion criteria were large ptotic breast and pinch test >2cm, while exclusion criteria were smoking >10 cigarettes/day, history of prior radiotherapy, patients supposedly requiring breast implants bigger than 550cc or post-mastectomy radiotherapy. Patients' data were collected through their electronic medical records. Both short- and long-term outcomes were reported.
RESULTS: Seventeen patients underwent Wise-pattern SRM followed by MODA-assisted, prepectoral, DTI-BR for a total of twenty-one breast reconstruction and fourteen matching procedures. Mean follow-up was 13.4 months (SD= ±3.67). No major complication was reported. Three (14.3%) reconstructed breasts had minor complications: 2 (9.5%) minimal (<1cm2) wound dehiscence and 1 (4.8%) de-epithelization of the skin at the T junction that were treated conservatively. Drainages gave mean output of 410.59 ml (SD= ±214.83) and were kept in place on average for 8.59 days (SD= ±3.45).
CONCLUSION: Few are the reports in the literature regarding DTI-BR following SRM and even fewer are those where BR was performed in the prepectoral space. Our work demonstrated the safety of prepectoral DTI-BR following SRM in selected patients in accordance with the "conservative reconstruction" principles. Furthermore, we confirmed the reliability of MODA in accordance with previously published works. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Entities:  

Keywords:  Acellular dermal matrix; Breast cancer; Breast reconstruction; Breast-conserving surgery; Conservative reconstruction

Year:  2021        PMID: 33782725     DOI: 10.1007/s00266-021-02231-5

Source DB:  PubMed          Journal:  Aesthetic Plast Surg        ISSN: 0364-216X            Impact factor:   2.326


  13 in total

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Authors:  Martina Ghetti; Elena Bondioli; Valeria Purpura; Giovanna Cenacchi; Paolo Ruscelli; Davide Melandri
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4.  How I Can Suspect of Mycobacteria Infection in Breast Implant Surgery?

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Journal:  World J Plast Surg       Date:  2016-09

5.  Reconstruction of the Ptotic Breast Using Wise Pattern Skin Deepithelialization.

Authors:  Michael K Newman
Journal:  Plast Reconstr Surg Glob Open       Date:  2016-11-21

Review 6.  One-Stage Immediate Breast Reconstruction: A Concise Review.

Authors:  Nicolò Bertozzi; Marianna Pesce; Pierluigi Santi; Edoardo Raposio
Journal:  Biomed Res Int       Date:  2017-10-02       Impact factor: 3.411

7.  The Aesthetic Items Scale: A Tool for the Evaluation of Aesthetic Outcome after Breast Reconstruction.

Authors:  Rieky E G Dikmans; Lauren E H Nene; Mark-Bram Bouman; Henrica C W de Vet; Marc A M Mureau; Marlon E Buncamper; Hay A H Winters; Marco J P F Ritt; Margriet G Mullender
Journal:  Plast Reconstr Surg Glob Open       Date:  2017-03-01

8.  Surgical Outcomes of Prepectoral Versus Subpectoral Implant-based Breast Reconstruction in Young Women.

Authors:  Oscar J Manrique; Joseph Banuelos; Amjed Abu-Ghname; Minh-Doan Nguyen; Nho V Tran; Jorys Martinez-Jorge; Christin Harless; Basel Sharaf; James W Jakub; Amy C Degnim; Judy C Boughey; Steven R Jacobson
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-03-13

9.  Wise Pattern Direct Implant Breast Reconstruction: A Review and Improved Outcomes Using Dermal Matrix.

Authors:  Harold I Friedman; Sarah Talebagha; Jarom Gilstrap; Mirsad Mujadzic; Elliott Chen
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-10-16

10.  Nipple-Sparing Mastectomy and Prepectoral Implant/Acellular Dermal Matrix Wrap Reconstruction in Large Ptotic Breasts.

Authors:  Haitham H Khalil; Marco N Malahias; Sherif Youssif; Tarek Ashour; Saif Rhobaye; Tahir Faroq
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-07-25
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