Literature DB >> 3377984

Alkaline phosphatase positive precursors of adipocytes in the human bone marrow.

P Bianco1, M Costantini, L C Dearden, E Bonucci.   

Abstract

Developing fat cells in the bone marrow of leukaemic patients treated with chemotherapy were found to be endowed with membrane-bound alkaline phosphatase. Since alkaline phosphatase is a cytochemical marker of 'reticular' cells, this observation provides cytochemical evidence that reticular cells may convert to adipocytes when marrow cellularity abruptly decreases.

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Year:  1988        PMID： 3377984     DOI： 10.1111/j.1365-2141.1988.tb04225.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN： 0007-1048            Impact factor:   6.998


  26 in total

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