Olutayo Ademola Adeleye1, Mbang Nyong Femi-Oyewo2, Oluyemisi Adebowale Bamiro2, Lateef Gbenga Bakre2, Akinyinka Alabi3, Joseph Senu Ashidi4, Olalekan Adeyinka Balogun-Agbaje2, Oluwakemi Mary Hassan5, Gbemisola Fakoya6. 1. Department of Pharmaceutics and Pharmaceutical Technology, Federal University Oye Ekiti, Oye-Ekiti, Ekiti State Nigeria. 2. Department of Pharmaceutics and Pharmaceutical Technology, Olabisi Onabanjo University, Ago-Iwoye, Ogun State Nigeria. 3. Department of Pharmacology, Olabisi Onabanjo University, Ago-Iwoye, Ogun State Nigeria. 4. Department of Plant Science, Olabisi Onabanjo University, Ago-Iwoye, Ogun State Nigeria. 5. Department of Pharmaceutical Microbiology, Olabisi Onabanjo University, Ago-Iwoye, Ogun State Nigeria. 6. Department of Pharmacology, University of Lagos, Lagos, Lagos State Nigeria.
Abstract
BACKGROUND: Ethnomedicine, a study of traditional medicine, is significant in drug discovery and development. African traditional medicine has been in existence for several thousands of years, and several drugs have been discovered and developed from it. MAIN TEXT: The deadly coronavirus disease 2019 (COVID-19) caused by a novel coronavirus known as SARS-CoV-2 has widely spread globally with high mortality and morbidity. Its prevention, treatment and management still pose a serious challenge. A drug for the cure of this disease is yet to be developed. The clinical management at present is based on symptomatic treatment as presented by individuals infected and this is by combination of more than two drugs such as antioxidants, anti-inflammatory, anti-pyretic, and anti-microbials. Literature search was performed through electronic searches of PubMed, Google Scholar, and several research reports including WHO technical documents and monographs. CONCLUSION: Drug discovery from herbs is essential and should be exploited for the discovery of drugs for the management of COVID-19. This review is aimed at identifying ethnomedicinal herbs available in Africa that could be used for the discovery and development of a drug for the prevention, treatment, and management of the novel coronavirus disease 2019.
BACKGROUND: Ethnomedicine, a study of traditional medicine, is significant in drug discovery and development. African traditional medicine has been in existence for several thousands of years, and several drugs have been discovered and developed from it. MAIN TEXT: The deadly coronavirus disease 2019 (COVID-19) caused by a novel coronavirus known as SARS-CoV-2 has widely spread globally with high mortality and morbidity. Its prevention, treatment and management still pose a serious challenge. A drug for the cure of this disease is yet to be developed. The clinical management at present is based on symptomatic treatment as presented by individuals infected and this is by combination of more than two drugs such as antioxidants, anti-inflammatory, anti-pyretic, and anti-microbials. Literature search was performed through electronic searches of PubMed, Google Scholar, and several research reports including WHO technical documents and monographs. CONCLUSION: Drug discovery from herbs is essential and should be exploited for the discovery of drugs for the management of COVID-19. This review is aimed at identifying ethnomedicinal herbs available in Africa that could be used for the discovery and development of a drug for the prevention, treatment, and management of the novel coronavirus disease 2019.
Authors: Agnes Gyuris; László Szlávik; János Minárovits; Andrea Vasas; Joseph Molnár; Judit Hohmann Journal: In Vivo Date: 2009 May-Jun Impact factor: 2.155
Authors: Aftab Ahmad; Asif Husain; Mohd Mujeeb; Shah Alam Khan; Abul Kalam Najmi; Nasir Ali Siddique; Zoheir A Damanhouri; Firoz Anwar Journal: Asian Pac J Trop Biomed Date: 2013-05
Authors: Yawen Zeng; Yuping Li; Jiazhen Yang; Xiaoying Pu; Juan Du; Xiaomeng Yang; Tao Yang; Shuming Yang Journal: Evid Based Complement Alternat Med Date: 2017-02-05 Impact factor: 2.629