Literature DB >> 3377785

KDN-glycoprotein: a novel deaminated neuraminic acid-rich glycoprotein isolated from vitelline envelope of rainbow trout eggs.

S Inoue1, A Kanamori, K Kitajima, Y Inoue.   

Abstract

A new acidic glycoprotein containing deaminated neuraminic acid (KDN = 3-deoxy-D-glycero-D-galacto-nonulosonic acid; greater than 50%, w/w) was isolated from vitelline envelope of the unfertilized eggs of rainbow trout (Salmo gairdneri). This glycoprotein is designated as "KDN-glycoprotein" because it contains only KDN but no sialic acid as the acidic carbohydrate moieties. Other major carbohydrate components of KDN-glycoprotein were Gal and GalNAc. Thr and Ala accounted for 71% (mol/mol) of amino acid composition. A possible occurrence of KDN-KDN linkages, i.e. oligoKDN groups has been suggested in the carbohydrate chains presumably linked O-glycosidically to the core protein.

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Year:  1988        PMID: 3377785     DOI: 10.1016/s0006-291x(88)81204-x

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  12 in total

1.  Structural analysis of a new series of oligosaccharide-alditols released by reductive beta-elimination from oviducal mucins of Rana utricularia.

Authors:  W Morelle; G Strecker
Journal:  Biochem J       Date:  1998-02-15       Impact factor: 3.857

2.  Oral ingestion of mannose alters the expression level of deaminoneuraminic acid (KDN) in mouse organs.

Authors:  Shinji Go; Chihiro Sato; Kimio Furuhata; Ken Kitajima
Journal:  Glycoconj J       Date:  2006-07       Impact factor: 2.916

3.  A 1H STD NMR spectroscopic investigation of sialylnucleoside mimetics as probes of CMP-Kdn synthetase.

Authors:  Thomas Haselhorst; Melanie Oschlies; Tareq Abu-Izneid; Milton J Kiefel; Joe Tiralongo; Anja K Münster-Kühnel; Rita Gerardy-Schahn; Mark von Itzstein
Journal:  Glycoconj J       Date:  2006-07       Impact factor: 2.916

Review 4.  KDN (deaminated neuraminic acid): dreamful past and exciting future of the newest member of the sialic acid family.

Authors:  Sadako Inoue; Ken Kitajima
Journal:  Glycoconj J       Date:  2006-07       Impact factor: 2.916

5.  A 1H NMR investigation of the hydrolysis of a synthetic substrate by KDN-sialidase from Crassostrea virginica.

Authors:  J C Wilson; D C Kong; Y T Li; M von Itzstein
Journal:  Glycoconj J       Date:  1996-12       Impact factor: 2.916

6.  Two different sialidases, KDN-sialidase and regular sialidase in the starfish Asterina pectinifera.

Authors:  J A Yuziuk; H Nakagawa; A Hasegawa; M Kiso; S C Li; Y T Li
Journal:  Biochem J       Date:  1996-05-01       Impact factor: 3.857

7.  1H-and 13C-n.m.r. spectroscopy of 2-oxo-3-deoxy-D-glycero-D- galactononulosonic acid-containing oligosaccharide-alditols bearing Lewis X, Lewis Y and A-Lewis Y determinants isolated from the jelly coat of Pleurodeles waltl eggs.

Authors:  G Strecker; J M Wieruszeski; J C Michalski; J Montreuil
Journal:  Biochem J       Date:  1992-11-01       Impact factor: 3.857

8.  Identification, characterization, and developmental expression of a novel alpha 2-->8-KDN-transferase which terminates elongation of alpha 2-->8-linked oligo-polysialic acid chain synthesis in trout egg polysialoglycoproteins.

Authors:  T Angata; S Kitazume; T Terada; K Kitajima; S Inoue; F A Troy; Y Inoue
Journal:  Glycoconj J       Date:  1994-10       Impact factor: 2.916

9.  Monoclonal antibody specific for alpha 2-->8-linked oligo deaminated neuraminic acid (KDN) sequences in glycoproteins. Preparation and characterization of a monoclonal antibody and its application in immunohistochemistry.

Authors:  A Kanamori; S Inoue; Z Xulei; C Zuber; J Roth; K Kitajima; J Ye; F A Troy; Y Inoue
Journal:  Histochemistry       Date:  1994-06

10.  Poly (alpha 2,8-deaminoneuraminic acid) is expressed in lung on a single 150-kDa glycoprotein and is an oncodevelopmental antigen.

Authors:  B Qu; M Ziak; C Zuber; J Roth
Journal:  Proc Natl Acad Sci U S A       Date:  1996-08-20       Impact factor: 11.205

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