Literature DB >> 33777695

Splenic infarction as a complication of covid-19 in a patient without respiratory symptoms: A case report and literature review.

Gustavo Rodrigues Alves Castro1, Iwan Augusto Collaço1, Caroline L Balcewicz Dal Bosco1, Gustavo Gusso Corrêa1, Giovana Balcewicz Dal Bosco1, Giovana Luiza Corrêa1.   

Abstract

INTRODUCTION: Multiple studies suggest that SARS-CoV-2 infection is associated with a pro-thrombotic state and thrombotic events have been recorded in several organs and systems. We report a patient with no respiratory symptoms, presented with abdominal pain and an extensive splenic infarction after COVID-19. CASE REPORT: A 67 year-old man was admitted to the emergency department with a moderate, dull, left-sided abdominal pain. The patient denied respiratory symptoms but referred contact with family members positive for COVID-19. He tested positive for COVID-19 and had increased D-dimer levels. Imaging studies revealed splenic infarcts and ground-glass opacities in bilateral pulmonary bases. He was treated with full-dose anticoagulation and was discharged home on oral Rivaroxaban. DISCUSSION: Although rare in the literature, cases of acute abdomen in COVID-19 patients associated with vascular infarctions have increased. Coagulopathy may be present even without clinical respiratory manifestations of the disease. Patients meeting disseminated intravascular coagulation criteria or with markedly elevated D-dimer may benefit from anticoagulant therapy.
CONCLUSION: Clinicians should suspect of abdominal visceral infarctions in COVID-19 patients presented with acute abdominal pain, despite the absence of respiratory symptoms.
© 2021 The Authors.

Entities:  

Keywords:  COVID-19; Disseminated intravascular coagulation; SARS-CoV-2; Splenic infarction

Year:  2021        PMID: 33777695      PMCID: PMC7980490          DOI: 10.1016/j.idcr.2021.e01062

Source DB:  PubMed          Journal:  IDCases        ISSN: 2214-2509


  10 in total

1.  Thromboinflammatory response in SARS-CoV-2 sepsis.

Authors:  Aniello Maiese; Giovanna Passaro; Alessandra DE Matteis; Valentina Fazio; La Russa Raffaele; Marco Di Paolo
Journal:  Med Leg J       Date:  2020-06-03

2.  [Pathological changes of the spleen in ten patients with coronavirus disease 2019(COVID-19) by postmortem needle autopsy].

Authors:  X Xu; X N Chang; H X Pan; H Su; B Huang; M Yang; D J Luo; M X Weng; L Ma; X Nie
Journal:  Zhonghua Bing Li Xue Za Zhi       Date:  2020-06-08

3.  Concomitant renal and splenic infarction as a complication of COVID-19: a case report and literature review.

Authors:  Maya Ramanathan; TeresaA Chueng; Edgar Fernandez; Jose Gonzales-Zamora
Journal:  Infez Med       Date:  2020-12-01

4.  Multisystemic Infarctions in COVID-19: Focus on the Spleen.

Authors:  Mariana Santos Leite Pessoa; Carla Franco Costa Lima; Ana Carla Farias Pimentel; José Carlos Godeiro Costa; Jorge Luis Bezerra Holanda
Journal:  Eur J Case Rep Intern Med       Date:  2020-06-03

5.  Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy.

Authors:  Ning Tang; Huan Bai; Xing Chen; Jiale Gong; Dengju Li; Ziyong Sun
Journal:  J Thromb Haemost       Date:  2020-04-27       Impact factor: 5.824

6.  Splenic infarcts as a rare manifestation of parvovirus B19 infection.

Authors:  Georgios Kranidiotis; Efrosini Efstratiadis; Georgios Kapsalakis; Georgios Loizos; Apostolos Bilis; Andreas Melidonis
Journal:  IDCases       Date:  2016-05-06

Review 7.  COVID-19: Are we dealing with a multisystem vasculopathy in disguise of a viral infection?

Authors:  Ritwick Mondal; Durjoy Lahiri; Shramana Deb; Deebya Bandyopadhyay; Gourav Shome; Sukanya Sarkar; Sudeb R Paria; Tirthankar Guha Thakurta; Pratibha Singla; Subhash C Biswas
Journal:  J Thromb Thrombolysis       Date:  2020-10       Impact factor: 5.221

8.  A case report on spontaneous hemoperitoneum in COVID-19 patient.

Authors:  Saurab Karki; Sushil Bahadur Rawal; Srijan Malla; Jyoti Rayamajhi; Bikash Bikram Thapa
Journal:  Int J Surg Case Rep       Date:  2020-09-14

9.  Acute Splenic Artery Thrombosis and Infarction Associated with COVID-19 Disease.

Authors:  Osama Qasim Agha; Ryan Berryman
Journal:  Case Rep Crit Care       Date:  2020-09-04

10.  COVID-19 coagulopathy: An in-depth analysis of the coagulation system.

Authors:  Reyes María Martín-Rojas; Gloria Pérez-Rus; Valeria Estefania Delgado-Pinos; Amalia Domingo-González; Isabel Regalado-Artamendi; Natalia Alba-Urdiales; Pablo Demelo-Rodríguez; Silvia Monsalvo; Gabriela Rodríguez-Macías; Monica Ballesteros; Santiago Osorio-Prendes; José Luis Díez-Martín; Cristina Pascual Izquierdo
Journal:  Eur J Haematol       Date:  2020-08-19       Impact factor: 3.674

  10 in total
  3 in total

Review 1.  Multiorgan Involvement in SARS-CoV-2 Infection: The Role of the Radiologist from Head to Toe.

Authors:  Davide Ippolito; Federica Vernuccio; Cesare Maino; Roberto Cannella; Teresa Giandola; Maria Ragusi; Vittorio Bigiogera; Carlo Capodaglio; Sandro Sironi
Journal:  Diagnostics (Basel)       Date:  2022-05-10

2.  Post-COVID-19 splenic infarction in a patient with chronic atrial fibrillation: A case report.

Authors:  Roham Sarmadian; Reza Ghasemikhah; Hossein Sarmadian; Mahmood Khosravi; Saeed Hassani
Journal:  Clin Case Rep       Date:  2022-07-11

3.  Splenic infarct in a COVID-19 patient under anticoagulant therapy with normal D-dimer levels.

Authors:  Semra Demirli Atıcı; Göksever Akpınar
Journal:  Int J Surg Case Rep       Date:  2022-02-18
  3 in total

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