| Literature DB >> 33775860 |
Naomi M Fettig1, Lisa C Osborne2.
Abstract
Multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE) are highly influenced by changes in the microbiota and of microbiota-derived metabolites, including short chain fatty acids, bile acids, and tryptophan derivatives. This review will discuss the effects of microbiota-derived metabolites on neuroinflammation driven by central nervous system-resident cells and peripheral immune cells, and their influence on outcomes of EAE and MS.Entities:
Keywords: Bile acids; Experimental autoimmune encephalitis (EAE); Microbiota; Multiple sclerosis (MS); Short chain fatty acids (SCFA); Tryptophan
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Year: 2021 PMID： 33775860 DOI： 10.1016/j.micinf.2021.104814
Source DB: PubMed Journal: Microbes Infect ISSN： 1286-4579 Impact factor: 2.700